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[Changes of pH and kinematic viscosity of the contents of gall-bladder at the pre-gallstone stage of cholelithiasis].
Georgian Med News 2005 Jul-Aug; (124-125):50-3GM

Abstract

The aim of the work was to study the indicators of pH and kinematic viscosity of the contents of the gall-bladder at receiving B-portion and their changes after a 7-hour period according to the biliary sediment of patients and to establish their link to the infection. Total 31 patients aged 25-55 with biliary sediment in lumens of their gall-bladders (a general group) and 5 healthy patients (a control group) were studied by us. In all cases the markers of the virus of Hepatitis B in blood serum were determined and ultrasonic examination of gall-bladder was carried out by us prior to the duodenal intubation. B-portion was subjected to bacteriological research for aerobes and anaerobs, and pH and kinematic viscosity (eta=mm(2)/sec) were determined. The patients from the control as well as from the general group after a 7-hour period were redetermined pH and Kinematic viscosity of B-portion. Kinematic viscosity was determined with a capillary viscosimeter, and pH was fixed by a method of potentiometer. Statistical treatment was undertaken by the method of ANOLA p<0,05. During the duodenal intubation the mean value of pH within the control group was fixed at 6.74, and the mean value of the kinematic viscosity was 1.34, and after a 7-hour period the same indicators constituted 6.87 and 1.35 mm(2)/sec, respectively. The same indicators within the general group during duodenal intubation were the following: 7.26 and 1.99 mm(2)/sec, and after a 7-hour period the same indicators were 7.78 and 2.19 mm(2)/sec, respectively. There was a significant statistical difference between the mean values of pH and kinematic viscosity of the contents of gall-bladder of the patients from the control and general groups. During a 7-hour period, there was also a significant statistical difference between the changes of the same indicators. The difference was even greater in case of infection. Following the above-mentioned we can conclude that in case of sediment in the lumen of gall-bladder, inclination of pH to alkalinity and increase in kinematic viscosity of the contents is one of the most important criteria of lithogenicity of gall-bladder contents, and one of the reasons for such changes is chronic infection of a gall-bladder.

Authors

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Pub Type(s)

English Abstract
Journal Article

Language

rus

PubMed ID

16148378

Citation

Sulaberidze, G T., et al. "[Changes of pH and Kinematic Viscosity of the Contents of Gall-bladder at the Pre-gallstone Stage of Cholelithiasis]." Georgian Medical News, 2005, pp. 50-3.
Sulaberidze GT, Rachvelishvili BK, Gelbakhiani GP, et al. [Changes of pH and kinematic viscosity of the contents of gall-bladder at the pre-gallstone stage of cholelithiasis]. Georgian Med News. 2005.
Sulaberidze, G. T., Rachvelishvili, B. K., Gelbakhiani, G. P., Zedania, Z. S., & Berchashvili, A. E. (2005). [Changes of pH and kinematic viscosity of the contents of gall-bladder at the pre-gallstone stage of cholelithiasis]. Georgian Medical News, (124-125), pp. 50-3.
Sulaberidze GT, et al. [Changes of pH and Kinematic Viscosity of the Contents of Gall-bladder at the Pre-gallstone Stage of Cholelithiasis]. Georgian Med News. 2005;(124-125)50-3. PubMed PMID: 16148378.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Changes of pH and kinematic viscosity of the contents of gall-bladder at the pre-gallstone stage of cholelithiasis]. AU - Sulaberidze,G T, AU - Rachvelishvili,B K, AU - Gelbakhiani,G P, AU - Zedania,Z S, AU - Berchashvili,A E, PY - 2005/9/9/pubmed PY - 2006/1/25/medline PY - 2005/9/9/entrez SP - 50 EP - 3 JF - Georgian medical news JO - Georgian Med News IS - 124-125 N2 - The aim of the work was to study the indicators of pH and kinematic viscosity of the contents of the gall-bladder at receiving B-portion and their changes after a 7-hour period according to the biliary sediment of patients and to establish their link to the infection. Total 31 patients aged 25-55 with biliary sediment in lumens of their gall-bladders (a general group) and 5 healthy patients (a control group) were studied by us. In all cases the markers of the virus of Hepatitis B in blood serum were determined and ultrasonic examination of gall-bladder was carried out by us prior to the duodenal intubation. B-portion was subjected to bacteriological research for aerobes and anaerobs, and pH and kinematic viscosity (eta=mm(2)/sec) were determined. The patients from the control as well as from the general group after a 7-hour period were redetermined pH and Kinematic viscosity of B-portion. Kinematic viscosity was determined with a capillary viscosimeter, and pH was fixed by a method of potentiometer. Statistical treatment was undertaken by the method of ANOLA p<0,05. During the duodenal intubation the mean value of pH within the control group was fixed at 6.74, and the mean value of the kinematic viscosity was 1.34, and after a 7-hour period the same indicators constituted 6.87 and 1.35 mm(2)/sec, respectively. The same indicators within the general group during duodenal intubation were the following: 7.26 and 1.99 mm(2)/sec, and after a 7-hour period the same indicators were 7.78 and 2.19 mm(2)/sec, respectively. There was a significant statistical difference between the mean values of pH and kinematic viscosity of the contents of gall-bladder of the patients from the control and general groups. During a 7-hour period, there was also a significant statistical difference between the changes of the same indicators. The difference was even greater in case of infection. Following the above-mentioned we can conclude that in case of sediment in the lumen of gall-bladder, inclination of pH to alkalinity and increase in kinematic viscosity of the contents is one of the most important criteria of lithogenicity of gall-bladder contents, and one of the reasons for such changes is chronic infection of a gall-bladder. SN - 1512-0112 UR - https://www.unboundmedicine.com/medline/citation/16148378/[Changes_of_pH_and_kinematic_viscosity_of_the_contents_of_gall_bladder_at_the_pre_gallstone_stage_of_cholelithiasis]_ L2 - https://medlineplus.gov/gallstones.html DB - PRIME DP - Unbound Medicine ER -