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Negative predictive value of sonography and mammography in patients with focal breast pain.
Breast J. 2005 Sep-Oct; 11(5):333-7.BJ

Abstract

The purpose of this study was to determine the negative predictive value of mammography and sonography in a population of patients with focal breast pain referred for imaging evaluation. Eighty-six consecutive patients with focal breast pain in the absence of a breast mass were retrospectively identified from an imaging database. The electronic inpatient and outpatient records for the 86 patients were reviewed. For patients who were diagnosed with breast cancer, pathology reports were reviewed to determine whether the painful area corresponded to the patient's cancer. In addition, patient records were linked to the institution's cancer registry. Of the 86 patients, 26 patients were lost to follow-up and did not appear in the institution's cancer registry. Four patients were diagnosed with breast carcinoma, two of whom had incidental cancers that were detected mammographically by microcalcifications and were separate from and unrelated to the area of pain. Seven patients underwent biopsy at the site of breast pain with benign diagnosis. Imaging and clinical follow-up for the 51 patients with benign or negative imaging at the site of pain showed no abnormality with a mean follow-up of 26.5 months. The negative predictive value of mammography and sonography in patients with breast pain was 100%. The negative predictive value of mammography and sonography for focal breast pain is high. Negative mammography and sonography can be reassuring to the treating clinician if follow-up is planned when physical examination is not suspicious. However, if physical examination is suspicious, biopsy should not be delayed.

Authors+Show Affiliations

Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California 90095-6952, USA. tumyan@ucla.eduNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

16174154

Citation

Tumyan, Lusine, et al. "Negative Predictive Value of Sonography and Mammography in Patients With Focal Breast Pain." The Breast Journal, vol. 11, no. 5, 2005, pp. 333-7.
Tumyan L, Hoyt AC, Bassett LW. Negative predictive value of sonography and mammography in patients with focal breast pain. Breast J. 2005;11(5):333-7.
Tumyan, L., Hoyt, A. C., & Bassett, L. W. (2005). Negative predictive value of sonography and mammography in patients with focal breast pain. The Breast Journal, 11(5), 333-7.
Tumyan L, Hoyt AC, Bassett LW. Negative Predictive Value of Sonography and Mammography in Patients With Focal Breast Pain. Breast J. 2005 Sep-Oct;11(5):333-7. PubMed PMID: 16174154.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Negative predictive value of sonography and mammography in patients with focal breast pain. AU - Tumyan,Lusine, AU - Hoyt,Anne C, AU - Bassett,Lawrence W, PY - 2005/9/22/pubmed PY - 2005/11/16/medline PY - 2005/9/22/entrez SP - 333 EP - 7 JF - The breast journal JO - Breast J VL - 11 IS - 5 N2 - The purpose of this study was to determine the negative predictive value of mammography and sonography in a population of patients with focal breast pain referred for imaging evaluation. Eighty-six consecutive patients with focal breast pain in the absence of a breast mass were retrospectively identified from an imaging database. The electronic inpatient and outpatient records for the 86 patients were reviewed. For patients who were diagnosed with breast cancer, pathology reports were reviewed to determine whether the painful area corresponded to the patient's cancer. In addition, patient records were linked to the institution's cancer registry. Of the 86 patients, 26 patients were lost to follow-up and did not appear in the institution's cancer registry. Four patients were diagnosed with breast carcinoma, two of whom had incidental cancers that were detected mammographically by microcalcifications and were separate from and unrelated to the area of pain. Seven patients underwent biopsy at the site of breast pain with benign diagnosis. Imaging and clinical follow-up for the 51 patients with benign or negative imaging at the site of pain showed no abnormality with a mean follow-up of 26.5 months. The negative predictive value of mammography and sonography in patients with breast pain was 100%. The negative predictive value of mammography and sonography for focal breast pain is high. Negative mammography and sonography can be reassuring to the treating clinician if follow-up is planned when physical examination is not suspicious. However, if physical examination is suspicious, biopsy should not be delayed. SN - 1075-122X UR - https://www.unboundmedicine.com/medline/citation/16174154/Negative_predictive_value_of_sonography_and_mammography_in_patients_with_focal_breast_pain_ L2 - https://doi.org/10.1111/j.1075-122X.2005.00018.x DB - PRIME DP - Unbound Medicine ER -