Tags

Type your tag names separated by a space and hit enter

The value of follow-up after acute Q fever infection.
J Infect. 2006 Apr; 52(4):e109-12.JI

Abstract

This is a case report of a 53-year-old woman involved in an outbreak of Q fever, in whom Q fever endocarditis was diagnosed 18 months after acute Q fever infection. At the time of diagnosis, she was completely asymptomatic and without screening for chronic Q fever, this severe potentially life-threatening infection would probably not have been recognised until significant valvular destruction had taken place. Early diagnosis enabled prompt, potentially curative medical treatment to start without the need for valvular heart surgery. The authors advocate that serological monitoring should be carried out every 4 months for a period of 2 years after acute Q fever and patients with high phase 1 IgG titres (>800) be investigated further and/or followed more closely depending on the clinical scenario. The case report also discusses the use of complement fixation testing in the diagnosis of Q fever endocarditis. The authors recommend that in cases of culture negative endocarditis, a single negative complement fixation test is not sufficient to exclude the diagnosis of Q fever endocarditis. Micro-immunofluorescence or repeat complement fixation testing is recommended when Q fever endocarditis is suspected clinically.

Authors+Show Affiliations

Microbiology Department, NPHS, UHW, Heath Park, Cardiff CF14 4XW, UK. brendan.healy@nphs.wales.nhs.ukNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

16181676

Citation

Healy, B, et al. "The Value of Follow-up After Acute Q Fever Infection." The Journal of Infection, vol. 52, no. 4, 2006, pp. e109-12.
Healy B, Llewelyn M, Westmoreland D, et al. The value of follow-up after acute Q fever infection. J Infect. 2006;52(4):e109-12.
Healy, B., Llewelyn, M., Westmoreland, D., Lloyd, G., & Brown, N. (2006). The value of follow-up after acute Q fever infection. The Journal of Infection, 52(4), e109-12.
Healy B, et al. The Value of Follow-up After Acute Q Fever Infection. J Infect. 2006;52(4):e109-12. PubMed PMID: 16181676.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The value of follow-up after acute Q fever infection. AU - Healy,B, AU - Llewelyn,M, AU - Westmoreland,D, AU - Lloyd,G, AU - Brown,N, Y1 - 2005/09/19/ PY - 2005/05/25/received PY - 2005/07/23/accepted PY - 2005/9/27/pubmed PY - 2007/7/21/medline PY - 2005/9/27/entrez SP - e109 EP - 12 JF - The Journal of infection JO - J Infect VL - 52 IS - 4 N2 - This is a case report of a 53-year-old woman involved in an outbreak of Q fever, in whom Q fever endocarditis was diagnosed 18 months after acute Q fever infection. At the time of diagnosis, she was completely asymptomatic and without screening for chronic Q fever, this severe potentially life-threatening infection would probably not have been recognised until significant valvular destruction had taken place. Early diagnosis enabled prompt, potentially curative medical treatment to start without the need for valvular heart surgery. The authors advocate that serological monitoring should be carried out every 4 months for a period of 2 years after acute Q fever and patients with high phase 1 IgG titres (>800) be investigated further and/or followed more closely depending on the clinical scenario. The case report also discusses the use of complement fixation testing in the diagnosis of Q fever endocarditis. The authors recommend that in cases of culture negative endocarditis, a single negative complement fixation test is not sufficient to exclude the diagnosis of Q fever endocarditis. Micro-immunofluorescence or repeat complement fixation testing is recommended when Q fever endocarditis is suspected clinically. SN - 1532-2742 UR - https://www.unboundmedicine.com/medline/citation/16181676/The_value_of_follow_up_after_acute_Q_fever_infection_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0163-4453(05)00214-8 DB - PRIME DP - Unbound Medicine ER -