Tags

Type your tag names separated by a space and hit enter

The association between cigarette smoking and colorectal polyp recurrence (United States).
Cancer Causes Control 2005; 16(9):1021-33CC

Abstract

OBJECTIVE

Although evidence exists linking smoking to precancerous colorectal adenomatous polyps, few studies have examined the association between cigarette smoking and recurrence of colorectal polyps. This association was investigated prospectively with data from the Polyp Prevention Trial.

METHODS

Cigarette smoking data were collected through baseline interviews. The study was completed by 1872 men and women with presence of adenomas at baseline colonoscopy. Multiple logistic regression analysis was used to examine the association between cigarette smoking and polyp recurrence (adenomatous and hyperplastic) up to four years from baseline.

RESULTS

Adenoma recurrence was not related to cigarette smoking. Current smokers had increased odds of hyperplastic polyps at follow-up compared to never smokers (OR 2.88, 95% CI 2.06-4.01). Current smoking was associated with subsequent distal (OR 3.44, 95% CI 2.38-4.95) and rectal (OR 3.53, 95% CI 2.15-5.78) hyperplastic polyps, but not subsequent proximal hyperplastic polyps. Cigarette smoking was associated with subsequent multiple and small size (4 mm) hyperplastic polyps. Significant linear trends were observed between development of subsequent hyperplastic polyps and all smoking variables.

CONCLUSIONS

Although no association with recurrent adenomas was observed, cigarette smoking was significantly associated with hyperplastic polyp development, except for those in the proximal colon. This prospective study confirms that cigarette smoking has a significant effect on the development of hyperplastic colorectal polyps.

Authors+Show Affiliations

Division of Population Sciences, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210-1240, USA. paskett-1@medctr.osu.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16184467

Citation

Paskett, Electra D., et al. "The Association Between Cigarette Smoking and Colorectal Polyp Recurrence (United States)." Cancer Causes & Control : CCC, vol. 16, no. 9, 2005, pp. 1021-33.
Paskett ED, Reeves KW, Pineau B, et al. The association between cigarette smoking and colorectal polyp recurrence (United States). Cancer Causes Control. 2005;16(9):1021-33.
Paskett, E. D., Reeves, K. W., Pineau, B., Albert, P. S., Caan, B., Hasson, M., ... Lanza, E. (2005). The association between cigarette smoking and colorectal polyp recurrence (United States). Cancer Causes & Control : CCC, 16(9), pp. 1021-33.
Paskett ED, et al. The Association Between Cigarette Smoking and Colorectal Polyp Recurrence (United States). Cancer Causes Control. 2005;16(9):1021-33. PubMed PMID: 16184467.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The association between cigarette smoking and colorectal polyp recurrence (United States). AU - Paskett,Electra D, AU - Reeves,Katherine W, AU - Pineau,Benoit, AU - Albert,Paul S, AU - Caan,Bette, AU - Hasson,Marsha, AU - Iber,Frank, AU - Kikendall,James Walter, AU - Lance,Peter, AU - Shike,Moshe, AU - Slattery,Martha L, AU - Weissfeld,Joel, AU - Kahle,Lisa, AU - Schatzkin,Arthur, AU - Lanza,Elaine, AU - ,, PY - 2004/12/15/received PY - 2005/04/29/accepted PY - 2005/9/27/pubmed PY - 2006/1/18/medline PY - 2005/9/27/entrez SP - 1021 EP - 33 JF - Cancer causes & control : CCC JO - Cancer Causes Control VL - 16 IS - 9 N2 - OBJECTIVE: Although evidence exists linking smoking to precancerous colorectal adenomatous polyps, few studies have examined the association between cigarette smoking and recurrence of colorectal polyps. This association was investigated prospectively with data from the Polyp Prevention Trial. METHODS: Cigarette smoking data were collected through baseline interviews. The study was completed by 1872 men and women with presence of adenomas at baseline colonoscopy. Multiple logistic regression analysis was used to examine the association between cigarette smoking and polyp recurrence (adenomatous and hyperplastic) up to four years from baseline. RESULTS: Adenoma recurrence was not related to cigarette smoking. Current smokers had increased odds of hyperplastic polyps at follow-up compared to never smokers (OR 2.88, 95% CI 2.06-4.01). Current smoking was associated with subsequent distal (OR 3.44, 95% CI 2.38-4.95) and rectal (OR 3.53, 95% CI 2.15-5.78) hyperplastic polyps, but not subsequent proximal hyperplastic polyps. Cigarette smoking was associated with subsequent multiple and small size (4 mm) hyperplastic polyps. Significant linear trends were observed between development of subsequent hyperplastic polyps and all smoking variables. CONCLUSIONS: Although no association with recurrent adenomas was observed, cigarette smoking was significantly associated with hyperplastic polyp development, except for those in the proximal colon. This prospective study confirms that cigarette smoking has a significant effect on the development of hyperplastic colorectal polyps. SN - 0957-5243 UR - https://www.unboundmedicine.com/medline/citation/16184467/The_association_between_cigarette_smoking_and_colorectal_polyp_recurrence__United_States__ L2 - https://doi.org/10.1007/s10552-005-0298-2 DB - PRIME DP - Unbound Medicine ER -