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[Immunological classification of 112 adult acute leukemia patients].
Zhonghua Xue Ye Xue Za Zhi. 2001 Dec; 22(12):633-5.ZX

Abstract

OBJECTIVE

To explore the criteria and significance of immunological classification in adult acute leukemias.

METHODS

One or two color monoclonal antibodies directly labeled with immunofluorescence were used to analyse the surface and cytoplasma antigens by flow cytometry, and an antibody integral system was developed for the immunologic classification.

RESULTS

One hundred and twelve adult acute leukemia cases were detected. (1) The undifferentiated phenotype account for 0.9%, simple 51.8%, variant 38.4% and mixed lineage 8.9%. (2) The abnormal expressions of antigen in variant and mixed lineage phenotype were CD7, CD33, CD10, CD13, CD19 and CD20, by order of decreased level.

CONCLUSION

The strict, numerical diagnostic criteria was very convenient and useful for immunophenotyping of adult acute leukemia.

Authors+Show Affiliations

Anhui Provincial Hospital, Hefei 230001, China.

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

16200710

Citation

Dai, H. "[Immunological Classification of 112 Adult Acute Leukemia Patients]." Zhonghua Xue Ye Xue Za Zhi = Zhonghua Xueyexue Zazhi, vol. 22, no. 12, 2001, pp. 633-5.
Dai H. [Immunological classification of 112 adult acute leukemia patients]. Zhonghua Xue Ye Xue Za Zhi. 2001;22(12):633-5.
Dai, H. (2001). [Immunological classification of 112 adult acute leukemia patients]. Zhonghua Xue Ye Xue Za Zhi = Zhonghua Xueyexue Zazhi, 22(12), 633-5.
Dai H. [Immunological Classification of 112 Adult Acute Leukemia Patients]. Zhonghua Xue Ye Xue Za Zhi. 2001;22(12):633-5. PubMed PMID: 16200710.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Immunological classification of 112 adult acute leukemia patients]. A1 - Dai,H, PY - 2005/10/5/pubmed PY - 2010/5/19/medline PY - 2005/10/5/entrez SP - 633 EP - 5 JF - Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi JO - Zhonghua Xue Ye Xue Za Zhi VL - 22 IS - 12 N2 - OBJECTIVE: To explore the criteria and significance of immunological classification in adult acute leukemias. METHODS: One or two color monoclonal antibodies directly labeled with immunofluorescence were used to analyse the surface and cytoplasma antigens by flow cytometry, and an antibody integral system was developed for the immunologic classification. RESULTS: One hundred and twelve adult acute leukemia cases were detected. (1) The undifferentiated phenotype account for 0.9%, simple 51.8%, variant 38.4% and mixed lineage 8.9%. (2) The abnormal expressions of antigen in variant and mixed lineage phenotype were CD7, CD33, CD10, CD13, CD19 and CD20, by order of decreased level. CONCLUSION: The strict, numerical diagnostic criteria was very convenient and useful for immunophenotyping of adult acute leukemia. SN - 0253-2727 UR - https://www.unboundmedicine.com/medline/citation/16200710/[Immunological_classification_of_112_adult_acute_leukemia_patients]_ L2 - https://medlineplus.gov/leukemia.html DB - PRIME DP - Unbound Medicine ER -