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[Intrathecal baclofen for children with chronic pain related to severe spasticity: advantages of tunneling the catheter in the testing phase].
Rev Esp Anestesiol Reanim. 2005 Aug-Sep; 52(7):395-400.RE

Abstract

OBJECTIVE

To document the effectiveness and safety of intrathecal baclofen administered through a tunneled catheter during a diagnostic procedure, prior to implantation of a subcutaneous pump, in children with chronic pain due to severe spasticity.

METHODS

This was a retrospective study of 6 children with intense chronic pain due to spasticity caused by cerebral palsy or genetic dystonia. Increasing doses of intrathecal baclofen in continuous perfusion through a tunneled catheter were tested.

RESULTS

Lumbar intrathecal catheters were tunneled for 48 to 80 hours in 5 males and 1 female aged 8 to 18 years old. Intrathecal baclofen was administered in continuous perfusion up to maximum rates that ranged between 105 and 570 microg/day. For 5 patients the score on the visual analog pain scale (0-10) changed from over 7 to 0 by the end of the test. In 2 patients, side effects of analgesia were noted, specifically sedation, bradycardia, and bradypnea. No serious complications, such as meningitis, spinal abscess, or hematoma, were reported. The families of 4 patients chose to accept implantation of a subcutaneous pump. Pump therapy remained effective and free of complications when checked 23 or 55 months after placement.

CONCLUSIONS

Performing a trial of increasing doses of intrathecal baclofen therapy in continuous perfusion through a tunneled catheter facilitated selection of patients for whom chronic administration of intrathecal baclofen is effective and free of complications.

Authors+Show Affiliations

Servicio de Anestesia-Reanimación y Unidad de Dolor Infantil, Hospital Universitario "La Paz", Madrid.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Evaluation Study
Journal Article

Language

spa

PubMed ID

16200919

Citation

Gómez-Hoz, T, et al. "[Intrathecal Baclofen for Children With Chronic Pain Related to Severe Spasticity: Advantages of Tunneling the Catheter in the Testing Phase]." Revista Espanola De Anestesiologia Y Reanimacion, vol. 52, no. 7, 2005, pp. 395-400.
Gómez-Hoz T, Reinoso-Barbero F, de Vicente JC, et al. [Intrathecal baclofen for children with chronic pain related to severe spasticity: advantages of tunneling the catheter in the testing phase]. Rev Esp Anestesiol Reanim. 2005;52(7):395-400.
Gómez-Hoz, T., Reinoso-Barbero, F., de Vicente, J. C., Duran, P., Campo, G., & Castro, L. E. (2005). [Intrathecal baclofen for children with chronic pain related to severe spasticity: advantages of tunneling the catheter in the testing phase]. Revista Espanola De Anestesiologia Y Reanimacion, 52(7), 395-400.
Gómez-Hoz T, et al. [Intrathecal Baclofen for Children With Chronic Pain Related to Severe Spasticity: Advantages of Tunneling the Catheter in the Testing Phase]. Rev Esp Anestesiol Reanim. 2005;52(7):395-400. PubMed PMID: 16200919.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Intrathecal baclofen for children with chronic pain related to severe spasticity: advantages of tunneling the catheter in the testing phase]. AU - Gómez-Hoz,T, AU - Reinoso-Barbero,F, AU - de Vicente,J C, AU - Duran,P, AU - Campo,G, AU - Castro,L E, PY - 2005/10/5/pubmed PY - 2005/10/27/medline PY - 2005/10/5/entrez SP - 395 EP - 400 JF - Revista espanola de anestesiologia y reanimacion JO - Rev Esp Anestesiol Reanim VL - 52 IS - 7 N2 - OBJECTIVE: To document the effectiveness and safety of intrathecal baclofen administered through a tunneled catheter during a diagnostic procedure, prior to implantation of a subcutaneous pump, in children with chronic pain due to severe spasticity. METHODS: This was a retrospective study of 6 children with intense chronic pain due to spasticity caused by cerebral palsy or genetic dystonia. Increasing doses of intrathecal baclofen in continuous perfusion through a tunneled catheter were tested. RESULTS: Lumbar intrathecal catheters were tunneled for 48 to 80 hours in 5 males and 1 female aged 8 to 18 years old. Intrathecal baclofen was administered in continuous perfusion up to maximum rates that ranged between 105 and 570 microg/day. For 5 patients the score on the visual analog pain scale (0-10) changed from over 7 to 0 by the end of the test. In 2 patients, side effects of analgesia were noted, specifically sedation, bradycardia, and bradypnea. No serious complications, such as meningitis, spinal abscess, or hematoma, were reported. The families of 4 patients chose to accept implantation of a subcutaneous pump. Pump therapy remained effective and free of complications when checked 23 or 55 months after placement. CONCLUSIONS: Performing a trial of increasing doses of intrathecal baclofen therapy in continuous perfusion through a tunneled catheter facilitated selection of patients for whom chronic administration of intrathecal baclofen is effective and free of complications. SN - 0034-9356 UR - https://www.unboundmedicine.com/medline/citation/16200919/[Intrathecal_baclofen_for_children_with_chronic_pain_related_to_severe_spasticity:_advantages_of_tunneling_the_catheter_in_the_testing_phase]_ L2 - http://www.diseaseinfosearch.org/result/6711 DB - PRIME DP - Unbound Medicine ER -