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Ciprofloxacin-induced acute generalized exanthematous pustulosis mimicking bullous drug eruption confirmed by a positive patch test.
Dermatology. 2005; 211(3):277-80.D

Abstract

We report the case of an 80-year-old woman presenting with ciprofloxacin-induced acute generalized exanthematous pustulosis (AGEP) confirmed by a positive patch test. Cutaneous morphology, course and histological findings were consistent with a definite diagnosis according to the AGEP validation score of the EuroSCAR study group. We point to the rarity of quinolone-induced AGEP and discuss immunological mechanisms, the value of in vivo and in vitro tests as well as the main differential diagnosis. Furthermore, we highlight in this particular case the challenging differentiation from bullous drug eruption.

Authors+Show Affiliations

Hausermann P
Department of Dermatology, University Hospital Basel, Switzerland.
Scherer K
No affiliation info available
Weber M
No affiliation info available
Bircher AJ
No affiliation info available

MeSH

Aged, 80 and overAnti-Bacterial AgentsCiprofloxacinDiagnosis, DifferentialDrug EruptionsExanthemaFemaleHumansPatch TestsSkin Diseases, Vesiculobullous

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

16205075

Citation

Hausermann, P, et al. "Ciprofloxacin-induced Acute Generalized Exanthematous Pustulosis Mimicking Bullous Drug Eruption Confirmed By a Positive Patch Test." Dermatology (Basel, Switzerland), vol. 211, no. 3, 2005, pp. 277-80.
Hausermann P, Scherer K, Weber M, et al. Ciprofloxacin-induced acute generalized exanthematous pustulosis mimicking bullous drug eruption confirmed by a positive patch test. Dermatology. 2005;211(3):277-80.
Hausermann, P., Scherer, K., Weber, M., & Bircher, A. J. (2005). Ciprofloxacin-induced acute generalized exanthematous pustulosis mimicking bullous drug eruption confirmed by a positive patch test. Dermatology (Basel, Switzerland), 211(3), 277-80.
Hausermann P, et al. Ciprofloxacin-induced Acute Generalized Exanthematous Pustulosis Mimicking Bullous Drug Eruption Confirmed By a Positive Patch Test. Dermatology. 2005;211(3):277-80. PubMed PMID: 16205075.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ciprofloxacin-induced acute generalized exanthematous pustulosis mimicking bullous drug eruption confirmed by a positive patch test. AU - Hausermann,P, AU - Scherer,K, AU - Weber,M, AU - Bircher,A J, PY - 2004/06/24/received PY - 2004/12/20/accepted PY - 2005/10/6/pubmed PY - 2006/1/20/medline PY - 2005/10/6/entrez SP - 277 EP - 80 JF - Dermatology (Basel, Switzerland) JO - Dermatology VL - 211 IS - 3 N2 - We report the case of an 80-year-old woman presenting with ciprofloxacin-induced acute generalized exanthematous pustulosis (AGEP) confirmed by a positive patch test. Cutaneous morphology, course and histological findings were consistent with a definite diagnosis according to the AGEP validation score of the EuroSCAR study group. We point to the rarity of quinolone-induced AGEP and discuss immunological mechanisms, the value of in vivo and in vitro tests as well as the main differential diagnosis. Furthermore, we highlight in this particular case the challenging differentiation from bullous drug eruption. SN - 1018-8665 UR - https://www.unboundmedicine.com/medline/citation/16205075/Ciprofloxacin_induced_acute_generalized_exanthematous_pustulosis_mimicking_bullous_drug_eruption_confirmed_by_a_positive_patch_test_ DB - PRIME DP - Unbound Medicine ER -