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Identification of new dicaffeoylquinic acids from Chrysanthemum morifolium and their antioxidant activities.
Planta Med. 2005 Sep; 71(9):871-6.PM

Abstract

Two new dicaffeoylquinic acids, 3,5-dicaffeoyl- epi-quinic acid (1) and 1,3-dicaffeoyl- epi-quinic acid (2), were isolated from Chrysanthemum morifolium Ramar together with six known dicaffeoylquinic acid derivatives and three flavonoids. The structures of the new compounds were elucidated using of spectroscopic methods. These compounds were assessed for antioxidant activities in the DPPH radical and superoxide anion radical scavenging systems. Most of the isolates showed strong antioxidant activities in these assay systems. Two new compounds showed potent superoxide anion radical scavenging activity (IC50 = 2.9 +/- 0.1 for 1 and 2.6 +/- 0.4 microg/mL for 2, respectively) in the xanthine/xanthine oxidase system as compared to quercetin and also showed potent DPPH radical scavenging activity (IC50 = 5.6 +/- 0.1 for 1 and 5.8 +/- 0.2 microg/mL for 2, respectively).

Authors+Show Affiliations

Medicinal Chemistry Research Center, Division of Life Sciences, Korea Institute of Science & Technology, Cheongryang, Seoul, Korea.No affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16206044

Citation

Kim, Hyoung Ja, and Yong Sup Lee. "Identification of New Dicaffeoylquinic Acids From Chrysanthemum Morifolium and Their Antioxidant Activities." Planta Medica, vol. 71, no. 9, 2005, pp. 871-6.
Kim HJ, Lee YS. Identification of new dicaffeoylquinic acids from Chrysanthemum morifolium and their antioxidant activities. Planta Med. 2005;71(9):871-6.
Kim, H. J., & Lee, Y. S. (2005). Identification of new dicaffeoylquinic acids from Chrysanthemum morifolium and their antioxidant activities. Planta Medica, 71(9), 871-6.
Kim HJ, Lee YS. Identification of New Dicaffeoylquinic Acids From Chrysanthemum Morifolium and Their Antioxidant Activities. Planta Med. 2005;71(9):871-6. PubMed PMID: 16206044.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Identification of new dicaffeoylquinic acids from Chrysanthemum morifolium and their antioxidant activities. AU - Kim,Hyoung Ja, AU - Lee,Yong Sup, PY - 2005/10/6/pubmed PY - 2005/12/24/medline PY - 2005/10/6/entrez SP - 871 EP - 6 JF - Planta medica JO - Planta Med VL - 71 IS - 9 N2 - Two new dicaffeoylquinic acids, 3,5-dicaffeoyl- epi-quinic acid (1) and 1,3-dicaffeoyl- epi-quinic acid (2), were isolated from Chrysanthemum morifolium Ramar together with six known dicaffeoylquinic acid derivatives and three flavonoids. The structures of the new compounds were elucidated using of spectroscopic methods. These compounds were assessed for antioxidant activities in the DPPH radical and superoxide anion radical scavenging systems. Most of the isolates showed strong antioxidant activities in these assay systems. Two new compounds showed potent superoxide anion radical scavenging activity (IC50 = 2.9 +/- 0.1 for 1 and 2.6 +/- 0.4 microg/mL for 2, respectively) in the xanthine/xanthine oxidase system as compared to quercetin and also showed potent DPPH radical scavenging activity (IC50 = 5.6 +/- 0.1 for 1 and 5.8 +/- 0.2 microg/mL for 2, respectively). SN - 0032-0943 UR - https://www.unboundmedicine.com/medline/citation/16206044/Identification_of_new_dicaffeoylquinic_acids_from_Chrysanthemum_morifolium_and_their_antioxidant_activities_ L2 - https://www.thieme-connect.com/DOI/DOI?10.1055/s-2005-873115 DB - PRIME DP - Unbound Medicine ER -