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Provisional diagnostic criteria for depression in Parkinson's disease: report of an NINDS/NIMH Work Group.
Mov Disord. 2006 Feb; 21(2):148-58.MD

Abstract

Mood disorders are the most common psychiatric problem associated with Parkinson's disease (PD), and have a negative impact on disability and quality of life. Accurate diagnosis of depressive disturbances in PD is critical and will facilitate the testing and use of new interventions; however, there are no clear diagnostic criteria for depressive disorders in PD. In their current form, strict Diagnostic and Statistical Manual of Mental Disorders (DSM) criteria are difficult to use in PD and require attribution of specific symptoms to PD itself or the depressive syndrome. Additionally, DSM criteria for major depression and dysthymia exclude perhaps half of PD patients with comorbid clinically significant depression. This review summarizes an NIH-sponsored workshop and describes recommended changes to DSM diagnostic criteria for depression for use in PD. Participants also recommended: (1) an inclusive approach to symptom assessment to enhance reliability of ratings in PD and avoid the need to attribute symptoms to a particular cause; (2) the inclusion of subsyndromal depression in clinical research studies of depression of PD; (3) the specification of timing of assessments for PD patients with motor fluctuations; and (4) the use of informants for cognitively impaired patients. The proposed diagnostic criteria are provisional and intended to be defined further and validated but provide a common starting point for clinical research in PD-associated depression.

Authors+Show Affiliations

Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA. lmarsh@jhmi.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

16211591

Citation

Marsh, Laura, et al. "Provisional Diagnostic Criteria for Depression in Parkinson's Disease: Report of an NINDS/NIMH Work Group." Movement Disorders : Official Journal of the Movement Disorder Society, vol. 21, no. 2, 2006, pp. 148-58.
Marsh L, McDonald WM, Cummings J, et al. Provisional diagnostic criteria for depression in Parkinson's disease: report of an NINDS/NIMH Work Group. Mov Disord. 2006;21(2):148-58.
Marsh, L., McDonald, W. M., Cummings, J., & Ravina, B. (2006). Provisional diagnostic criteria for depression in Parkinson's disease: report of an NINDS/NIMH Work Group. Movement Disorders : Official Journal of the Movement Disorder Society, 21(2), 148-58.
Marsh L, et al. Provisional Diagnostic Criteria for Depression in Parkinson's Disease: Report of an NINDS/NIMH Work Group. Mov Disord. 2006;21(2):148-58. PubMed PMID: 16211591.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Provisional diagnostic criteria for depression in Parkinson's disease: report of an NINDS/NIMH Work Group. AU - Marsh,Laura, AU - McDonald,William M, AU - Cummings,Jeffrey, AU - Ravina,Bernard, AU - ,, PY - 2005/10/8/pubmed PY - 2006/9/26/medline PY - 2005/10/8/entrez SP - 148 EP - 58 JF - Movement disorders : official journal of the Movement Disorder Society JO - Mov Disord VL - 21 IS - 2 N2 - Mood disorders are the most common psychiatric problem associated with Parkinson's disease (PD), and have a negative impact on disability and quality of life. Accurate diagnosis of depressive disturbances in PD is critical and will facilitate the testing and use of new interventions; however, there are no clear diagnostic criteria for depressive disorders in PD. In their current form, strict Diagnostic and Statistical Manual of Mental Disorders (DSM) criteria are difficult to use in PD and require attribution of specific symptoms to PD itself or the depressive syndrome. Additionally, DSM criteria for major depression and dysthymia exclude perhaps half of PD patients with comorbid clinically significant depression. This review summarizes an NIH-sponsored workshop and describes recommended changes to DSM diagnostic criteria for depression for use in PD. Participants also recommended: (1) an inclusive approach to symptom assessment to enhance reliability of ratings in PD and avoid the need to attribute symptoms to a particular cause; (2) the inclusion of subsyndromal depression in clinical research studies of depression of PD; (3) the specification of timing of assessments for PD patients with motor fluctuations; and (4) the use of informants for cognitively impaired patients. The proposed diagnostic criteria are provisional and intended to be defined further and validated but provide a common starting point for clinical research in PD-associated depression. SN - 0885-3185 UR - https://www.unboundmedicine.com/medline/citation/16211591/Provisional_diagnostic_criteria_for_depression_in_Parkinson's_disease:_report_of_an_NINDS/NIMH_Work_Group_ L2 - https://doi.org/10.1002/mds.20723 DB - PRIME DP - Unbound Medicine ER -