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Prevalence and clinical characteristics of restless legs syndrome in Japanese patients with Parkinson's disease.
Mov Disord. 2006 Mar; 21(3):380-4.MD

Abstract

To explore the clinical significance of restless legs syndrome (RLS) in Parkinson's disease (PD) and the causal relationship between these two disorders, we made a comparison of both the prevalence of RLS and the severity of sleep disturbance manifested on the Pittsburg Sleep Quality Index (PSQI) between patients with PD (n=165) and age- and sex-matched control subjects (n=131). The prevalence of RLS diagnosed by clinical interview was significantly higher in PD patients than in control subjects (12% vs. 2.3%). PSQI score was significantly higher in PD patients with RLS than in both patients without RLS and controls. However, PSQI score was not statistically different between the latter two groups. Among the PD patients with RLS, only 2 had a positive family history of RLS. Only 3 PD patients had requested treatment for the disorder. Our results emphasize the etiological link between RLS and PD in a Japanese cohort, and the existence of RLS is thought to be one of the most important factors aggravating sleep disturbance in PD, despite the low RLS severity.

Authors+Show Affiliations

Department of Neurology, Institute of Neurological Sciences, Tottori University Faculty of Medicine, Yonago, Japan. ZVS03523@nifty.ne.jpNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16211604

Citation

Nomura, Takashi, et al. "Prevalence and Clinical Characteristics of Restless Legs Syndrome in Japanese Patients With Parkinson's Disease." Movement Disorders : Official Journal of the Movement Disorder Society, vol. 21, no. 3, 2006, pp. 380-4.
Nomura T, Inoue Y, Miyake M, et al. Prevalence and clinical characteristics of restless legs syndrome in Japanese patients with Parkinson's disease. Mov Disord. 2006;21(3):380-4.
Nomura, T., Inoue, Y., Miyake, M., Yasui, K., & Nakashima, K. (2006). Prevalence and clinical characteristics of restless legs syndrome in Japanese patients with Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society, 21(3), 380-4.
Nomura T, et al. Prevalence and Clinical Characteristics of Restless Legs Syndrome in Japanese Patients With Parkinson's Disease. Mov Disord. 2006;21(3):380-4. PubMed PMID: 16211604.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence and clinical characteristics of restless legs syndrome in Japanese patients with Parkinson's disease. AU - Nomura,Takashi, AU - Inoue,Yuichi, AU - Miyake,Masahiro, AU - Yasui,Kenichi, AU - Nakashima,Kenji, PY - 2005/10/8/pubmed PY - 2006/8/4/medline PY - 2005/10/8/entrez SP - 380 EP - 4 JF - Movement disorders : official journal of the Movement Disorder Society JO - Mov Disord VL - 21 IS - 3 N2 - To explore the clinical significance of restless legs syndrome (RLS) in Parkinson's disease (PD) and the causal relationship between these two disorders, we made a comparison of both the prevalence of RLS and the severity of sleep disturbance manifested on the Pittsburg Sleep Quality Index (PSQI) between patients with PD (n=165) and age- and sex-matched control subjects (n=131). The prevalence of RLS diagnosed by clinical interview was significantly higher in PD patients than in control subjects (12% vs. 2.3%). PSQI score was significantly higher in PD patients with RLS than in both patients without RLS and controls. However, PSQI score was not statistically different between the latter two groups. Among the PD patients with RLS, only 2 had a positive family history of RLS. Only 3 PD patients had requested treatment for the disorder. Our results emphasize the etiological link between RLS and PD in a Japanese cohort, and the existence of RLS is thought to be one of the most important factors aggravating sleep disturbance in PD, despite the low RLS severity. SN - 0885-3185 UR - https://www.unboundmedicine.com/medline/citation/16211604/Prevalence_and_clinical_characteristics_of_restless_legs_syndrome_in_Japanese_patients_with_Parkinson's_disease_ L2 - https://doi.org/10.1002/mds.20734 DB - PRIME DP - Unbound Medicine ER -