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Glycemic load, glycemic index, and the risk of breast cancer among Mexican women.
Cancer Causes Control 2005; 16(10):1165-9CC

Abstract

OBJECTIVE

The amount and composition of dietary carbohydrates is a major determinant of postprandial blood glucose and insulin, and risk of breast cancer has been positively associated with plasma levels of insulin and insulin-like growth factor 1. We sought to evaluate dietary glycemic load (GL) and overall glycemic index (GI) in relation to breast cancer risk in Mexican women.

METHODS

We examined dietary GL and overall GI and breast cancer risk among 475 women with histologically-confirmed breast cancer and a random sample of 1391 women from Mexico City households. Diet was assessed using a food frequency questionnaire adapted to the Mexican population.

RESULTS

The multivariate adjusted or for all women comparing the highest quartile of dietary GL with the lowest quartile was 1.62 (95% CI 1.13-2.32; p-test for trend = 0.02) with a significant trend. In postmenopausal women, the multivariate adjusted or comparing the extreme quartiles was 2.18 (95% CI 1.34-3.55; p-test for trend=0.005). Overall GI was not significantly associated with risk of breast cancer.

CONCLUSION

High intake of rapidly absorbed carbohydrate appears to play an important role in the risk of breast cancer in Mexican women.

Authors+Show Affiliations

Instituto Nacional de Salud Publica, Cuernavaca, México.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

16215866

Citation

Lajous, Martin, et al. "Glycemic Load, Glycemic Index, and the Risk of Breast Cancer Among Mexican Women." Cancer Causes & Control : CCC, vol. 16, no. 10, 2005, pp. 1165-9.
Lajous M, Willett W, Lazcano-Ponce E, et al. Glycemic load, glycemic index, and the risk of breast cancer among Mexican women. Cancer Causes Control. 2005;16(10):1165-9.
Lajous, M., Willett, W., Lazcano-Ponce, E., Sanchez-Zamorano, L. M., Hernandez-Avila, M., & Romieu, I. (2005). Glycemic load, glycemic index, and the risk of breast cancer among Mexican women. Cancer Causes & Control : CCC, 16(10), pp. 1165-9.
Lajous M, et al. Glycemic Load, Glycemic Index, and the Risk of Breast Cancer Among Mexican Women. Cancer Causes Control. 2005;16(10):1165-9. PubMed PMID: 16215866.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Glycemic load, glycemic index, and the risk of breast cancer among Mexican women. AU - Lajous,Martin, AU - Willett,Walter, AU - Lazcano-Ponce,Eduardo, AU - Sanchez-Zamorano,Luisa Maria, AU - Hernandez-Avila,Mauricio, AU - Romieu,Isabelle, PY - 2004/02/10/received PY - 2005/06/15/accepted PY - 2005/10/11/pubmed PY - 2006/3/1/medline PY - 2005/10/11/entrez SP - 1165 EP - 9 JF - Cancer causes & control : CCC JO - Cancer Causes Control VL - 16 IS - 10 N2 - OBJECTIVE: The amount and composition of dietary carbohydrates is a major determinant of postprandial blood glucose and insulin, and risk of breast cancer has been positively associated with plasma levels of insulin and insulin-like growth factor 1. We sought to evaluate dietary glycemic load (GL) and overall glycemic index (GI) in relation to breast cancer risk in Mexican women. METHODS: We examined dietary GL and overall GI and breast cancer risk among 475 women with histologically-confirmed breast cancer and a random sample of 1391 women from Mexico City households. Diet was assessed using a food frequency questionnaire adapted to the Mexican population. RESULTS: The multivariate adjusted or for all women comparing the highest quartile of dietary GL with the lowest quartile was 1.62 (95% CI 1.13-2.32; p-test for trend = 0.02) with a significant trend. In postmenopausal women, the multivariate adjusted or comparing the extreme quartiles was 2.18 (95% CI 1.34-3.55; p-test for trend=0.005). Overall GI was not significantly associated with risk of breast cancer. CONCLUSION: High intake of rapidly absorbed carbohydrate appears to play an important role in the risk of breast cancer in Mexican women. SN - 0957-5243 UR - https://www.unboundmedicine.com/medline/citation/16215866/Glycemic_load_glycemic_index_and_the_risk_of_breast_cancer_among_Mexican_women_ L2 - https://doi.org/10.1007/s10552-005-0355-x DB - PRIME DP - Unbound Medicine ER -