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Site of origin of nasal polyps: relevance to pathogenesis and management.
Rhinology. 2005 Sep; 43(3):180-4.R

Abstract

The site of origin of sino-nasal polyps was documented in 113 consecutive patients undergoing functional endoscopic sinus surgery (FESS). These patients were assigned pre-operatively to 4 clinical groups according to the out-patient recorded endoscopic appearance of their nasal cavities; chronic rhinosinusitis without polyps (CRSS) n=35, grade 1 polyps n=28, grade 2 polyps n=30 and grade 3 polyps n=20. In the group of patients diagnosed with polyps pre-operatively, 97.4% had polyps originating in the anterior ethmoid complex, of which 89.7% had polyps originating in the anterior ethmoidal cells and over 60% had polyps specifically originating from each of the following sites: the uncinate or infundibulum, the posterior ethmoid sinus, the frontal recess and the face of the bulla ethmoidalis. In the group diagnosed pre-operatively as CRSS without polyps, polyps were found in 60% of patients within the sinuses during surgery. In summary, our findings suggest that polyps originate from the middle meatus, and may be found at surgery when undetectable at pre-operative endoscopy.

Authors+Show Affiliations

Andrews AE
ENT Department, Royal Surrey County Hospital, Egerton Road, Guildford, United Kingdom.
Bryson JM
No affiliation info available
Rowe-Jones JM
No affiliation info available

MeSH

AdultChronic DiseaseEndoscopyFemaleHumansMaleMiddle AgedNasal MucosaNasal PolypsParanasal SinusesRhinitisSeverity of Illness IndexSinusitis

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16218510

Clinical Trial Links

Role of Doxycycline in Chronic Rhinosinusitis With Nasal Polyps

Citation

Andrews, A E., et al. "Site of Origin of Nasal Polyps: Relevance to Pathogenesis and Management." Rhinology, vol. 43, no. 3, 2005, pp. 180-4.
Andrews AE, Bryson JM, Rowe-Jones JM. Site of origin of nasal polyps: relevance to pathogenesis and management. Rhinology. 2005;43(3):180-4.
Andrews, A. E., Bryson, J. M., & Rowe-Jones, J. M. (2005). Site of origin of nasal polyps: relevance to pathogenesis and management. Rhinology, 43(3), 180-4.
Andrews AE, Bryson JM, Rowe-Jones JM. Site of Origin of Nasal Polyps: Relevance to Pathogenesis and Management. Rhinology. 2005;43(3):180-4. PubMed PMID: 16218510.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Site of origin of nasal polyps: relevance to pathogenesis and management. AU - Andrews,A E, AU - Bryson,J M, AU - Rowe-Jones,J M, PY - 2005/10/13/pubmed PY - 2006/1/4/medline PY - 2005/10/13/entrez SP - 180 EP - 4 JF - Rhinology JO - Rhinology VL - 43 IS - 3 N2 - The site of origin of sino-nasal polyps was documented in 113 consecutive patients undergoing functional endoscopic sinus surgery (FESS). These patients were assigned pre-operatively to 4 clinical groups according to the out-patient recorded endoscopic appearance of their nasal cavities; chronic rhinosinusitis without polyps (CRSS) n=35, grade 1 polyps n=28, grade 2 polyps n=30 and grade 3 polyps n=20. In the group of patients diagnosed with polyps pre-operatively, 97.4% had polyps originating in the anterior ethmoid complex, of which 89.7% had polyps originating in the anterior ethmoidal cells and over 60% had polyps specifically originating from each of the following sites: the uncinate or infundibulum, the posterior ethmoid sinus, the frontal recess and the face of the bulla ethmoidalis. In the group diagnosed pre-operatively as CRSS without polyps, polyps were found in 60% of patients within the sinuses during surgery. In summary, our findings suggest that polyps originate from the middle meatus, and may be found at surgery when undetectable at pre-operative endoscopy. SN - 0300-0729 UR - https://www.unboundmedicine.com/medline/citation/16218510/Site_of_origin_of_nasal_polyps:_relevance_to_pathogenesis_and_management_ DB - PRIME DP - Unbound Medicine ER -