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Acute trichinellosis in children compared with adults.
Pediatr Infect Dis J 2005; 24(10):897-900PI

Abstract

OBJECTIVES

Trichinellosis is a cosmopolitan parasite infection caused by Trichinella nematodes that is acquired from consumption of raw meat from several animal species. Knowledge of the clinical pattern and laboratory features of the disease in childhood is limited. The purpose is to study the clinical pattern of trichinellosis caused by Trichinella britovi in children and to compare it in household adults.

METHODS

We evaluated all children up to 17 years of age and their adult householders exposed to the consumption of infected meat during an outbreak of trichinellosis. A questionnaire was developed to record clinical data. The blood sample was collected for blood count, muscle enzymes, serum electrolytes, albumin and serology. All exposed children were treated with mebendazole, and severe symptomatic patients received prednisolone. Clinical and laboratory presentations and outcome were recorded. To evaluate the clinical picture of trichinellosis in childhood, clinical and laboratory findings were compared between children and household adults with a confirmed diagnosis who consumed the same amount of infected meat.

RESULTS

In 47 (62%) of 76 children with suspected trichinellosis, the diagnosis was serologically confirmed. The main clinical and laboratory findings in children were fever, abdominal pain, myalgia, facial and/or eyelid edema, rash, eosinophilia and increased muscular enzymes. The incubation period was similar in children and adults, but myalgia (66% versus 96%, P < 0.01), facial and/or eyelid edema (57% versus 86%, P < 0.05), eosinophilia (52% versus 96%, P < 0.01) and increased serum creatine kinase (38% versus 79%, P < 0.01) were less common in children than in adults. Seroconversion occurred in fewer children than adults, but the difference was not statistically significant.

CONCLUSIONS

T. britovi infection shows a benign course and a milder clinical picture in children than in adults who consumed the same amount of infected meat.

Authors+Show Affiliations

Department of Pediatrics, Dokuz Eylul University, School of Medicine, Izmir, Turkey.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

16220088

Citation

Ozdemir, Durgul, et al. "Acute Trichinellosis in Children Compared With Adults." The Pediatric Infectious Disease Journal, vol. 24, no. 10, 2005, pp. 897-900.
Ozdemir D, Ozkan H, Akkoc N, et al. Acute trichinellosis in children compared with adults. Pediatr Infect Dis J. 2005;24(10):897-900.
Ozdemir, D., Ozkan, H., Akkoc, N., Onen, F., Gurler, O., Sari, I., ... Pozio, E. (2005). Acute trichinellosis in children compared with adults. The Pediatric Infectious Disease Journal, 24(10), pp. 897-900.
Ozdemir D, et al. Acute Trichinellosis in Children Compared With Adults. Pediatr Infect Dis J. 2005;24(10):897-900. PubMed PMID: 16220088.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acute trichinellosis in children compared with adults. AU - Ozdemir,Durgul, AU - Ozkan,Hasan, AU - Akkoc,Nurullah, AU - Onen,Fatos, AU - Gurler,Oguz, AU - Sari,Ismail, AU - Akar,Servet, AU - Birlik,Merih, AU - Kargi,Aydanur, AU - Ozer,Erdener, AU - Pozio,Edoardo, PY - 2005/10/13/pubmed PY - 2006/1/6/medline PY - 2005/10/13/entrez SP - 897 EP - 900 JF - The Pediatric infectious disease journal JO - Pediatr. Infect. Dis. J. VL - 24 IS - 10 N2 - OBJECTIVES: Trichinellosis is a cosmopolitan parasite infection caused by Trichinella nematodes that is acquired from consumption of raw meat from several animal species. Knowledge of the clinical pattern and laboratory features of the disease in childhood is limited. The purpose is to study the clinical pattern of trichinellosis caused by Trichinella britovi in children and to compare it in household adults. METHODS: We evaluated all children up to 17 years of age and their adult householders exposed to the consumption of infected meat during an outbreak of trichinellosis. A questionnaire was developed to record clinical data. The blood sample was collected for blood count, muscle enzymes, serum electrolytes, albumin and serology. All exposed children were treated with mebendazole, and severe symptomatic patients received prednisolone. Clinical and laboratory presentations and outcome were recorded. To evaluate the clinical picture of trichinellosis in childhood, clinical and laboratory findings were compared between children and household adults with a confirmed diagnosis who consumed the same amount of infected meat. RESULTS: In 47 (62%) of 76 children with suspected trichinellosis, the diagnosis was serologically confirmed. The main clinical and laboratory findings in children were fever, abdominal pain, myalgia, facial and/or eyelid edema, rash, eosinophilia and increased muscular enzymes. The incubation period was similar in children and adults, but myalgia (66% versus 96%, P < 0.01), facial and/or eyelid edema (57% versus 86%, P < 0.05), eosinophilia (52% versus 96%, P < 0.01) and increased serum creatine kinase (38% versus 79%, P < 0.01) were less common in children than in adults. Seroconversion occurred in fewer children than adults, but the difference was not statistically significant. CONCLUSIONS: T. britovi infection shows a benign course and a milder clinical picture in children than in adults who consumed the same amount of infected meat. SN - 0891-3668 UR - https://www.unboundmedicine.com/medline/citation/16220088/Acute_trichinellosis_in_children_compared_with_adults_ L2 - http://Insights.ovid.com/pubmed?pmid=16220088 DB - PRIME DP - Unbound Medicine ER -