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Milk thistle.
Am Fam Physician 2005; 72(7):1285-8AF

Abstract

Milk thistle has been used as a cytoprotectant for the treatment of liver disease, for the treatment and prevention of cancer, and as a supportive treatment of Amanita phalloides poisoning. Clinical studies are largely heterogeneous and contradictory. Aside from mild gastrointestinal distress and allergic reactions, side effects are rare, and serious toxicity rarely has been reported. In an oral form standardized to contain 70 to 80 percent silymarin, milk thistle appears to be safe for up to 41 months of use. Significant drug reactions have not been reported. Clinical studies in oncology and infectious disease that are under way will help determine the efficacy and effectiveness of milk thistle.

Authors+Show Affiliations

Albert Einstein College of Medicine of Yeshiva University, Bronx, New York.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

16225032

Citation

Rainone, Francine. "Milk Thistle." American Family Physician, vol. 72, no. 7, 2005, pp. 1285-8.
Rainone F. Milk thistle. Am Fam Physician. 2005;72(7):1285-8.
Rainone, F. (2005). Milk thistle. American Family Physician, 72(7), pp. 1285-8.
Rainone F. Milk Thistle. Am Fam Physician. 2005 Oct 1;72(7):1285-8. PubMed PMID: 16225032.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Milk thistle. A1 - Rainone,Francine, PY - 2005/10/18/pubmed PY - 2005/11/4/medline PY - 2005/10/18/entrez SP - 1285 EP - 8 JF - American family physician JO - Am Fam Physician VL - 72 IS - 7 N2 - Milk thistle has been used as a cytoprotectant for the treatment of liver disease, for the treatment and prevention of cancer, and as a supportive treatment of Amanita phalloides poisoning. Clinical studies are largely heterogeneous and contradictory. Aside from mild gastrointestinal distress and allergic reactions, side effects are rare, and serious toxicity rarely has been reported. In an oral form standardized to contain 70 to 80 percent silymarin, milk thistle appears to be safe for up to 41 months of use. Significant drug reactions have not been reported. Clinical studies in oncology and infectious disease that are under way will help determine the efficacy and effectiveness of milk thistle. SN - 0002-838X UR - https://www.unboundmedicine.com/medline/citation/16225032/Milk_thistle_ L2 - http://www.aafp.org/link_out?pmid=16225032 DB - PRIME DP - Unbound Medicine ER -