Tags

Type your tag names separated by a space and hit enter

Does facial sebum excretion really affect the development of acne?
Br J Dermatol 2005; 153(5):919-24BJ

Abstract

BACKGROUND

It is generally accepted that the severity of acne is correlated with facial sebum secretion. However, previous studies on the relation between seborrhoea and the development of acne did not consider topographical differences in facial sebum secretion and used relatively vague acne severity grading systems.

OBJECTIVES

To elucidate the relation between topographical variations in facial sebum secretion and the severity of acne in women.

METHODS

Forty-six female controls and 46 women with acne were included in this study. The Sebumeter was used to measure facial sebum secretion in the following facial areas: forehead, nose, chin, and right and left cheek. We counted noninflammatory comedones and inflammatory acne lesions in the same areas. We compared sebum secretion between patients with acne and controls, and analysed the relation between the quantity of sebum secreted and the number of acne lesions.

RESULTS

Sebum secretions in the whole face and in the T- and U-zones (areas of high and low sebum secretion, respectively) were higher in patients with acne than in controls. There was no correlation between sebum quantity and acne lesion count in most facial regions.

CONCLUSIONS

Increased levels of facial sebum secretion were observed in patients with acne. Our findings indicate that increased sebum levels do not directly cause development of acne lesions.

Authors+Show Affiliations

Department of Dermatology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 300 Gumi-dong, Bundang-gu, Seongnam-si, Kyounggi-do 463-707, Korea. swyoun@snu.ac.krNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16225600

Citation

Youn, S-W, et al. "Does Facial Sebum Excretion Really Affect the Development of Acne?" The British Journal of Dermatology, vol. 153, no. 5, 2005, pp. 919-24.
Youn SW, Park ES, Lee DH, et al. Does facial sebum excretion really affect the development of acne? Br J Dermatol. 2005;153(5):919-24.
Youn, S. W., Park, E. S., Lee, D. H., Huh, C. H., & Park, K. C. (2005). Does facial sebum excretion really affect the development of acne? The British Journal of Dermatology, 153(5), pp. 919-24.
Youn SW, et al. Does Facial Sebum Excretion Really Affect the Development of Acne. Br J Dermatol. 2005;153(5):919-24. PubMed PMID: 16225600.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Does facial sebum excretion really affect the development of acne? AU - Youn,S-W, AU - Park,E-S, AU - Lee,D-H, AU - Huh,C-H, AU - Park,K-C, PY - 2005/10/18/pubmed PY - 2006/2/4/medline PY - 2005/10/18/entrez SP - 919 EP - 24 JF - The British journal of dermatology JO - Br. J. Dermatol. VL - 153 IS - 5 N2 - BACKGROUND: It is generally accepted that the severity of acne is correlated with facial sebum secretion. However, previous studies on the relation between seborrhoea and the development of acne did not consider topographical differences in facial sebum secretion and used relatively vague acne severity grading systems. OBJECTIVES: To elucidate the relation between topographical variations in facial sebum secretion and the severity of acne in women. METHODS: Forty-six female controls and 46 women with acne were included in this study. The Sebumeter was used to measure facial sebum secretion in the following facial areas: forehead, nose, chin, and right and left cheek. We counted noninflammatory comedones and inflammatory acne lesions in the same areas. We compared sebum secretion between patients with acne and controls, and analysed the relation between the quantity of sebum secreted and the number of acne lesions. RESULTS: Sebum secretions in the whole face and in the T- and U-zones (areas of high and low sebum secretion, respectively) were higher in patients with acne than in controls. There was no correlation between sebum quantity and acne lesion count in most facial regions. CONCLUSIONS: Increased levels of facial sebum secretion were observed in patients with acne. Our findings indicate that increased sebum levels do not directly cause development of acne lesions. SN - 0007-0963 UR - https://www.unboundmedicine.com/medline/citation/16225600/Does_facial_sebum_excretion_really_affect_the_development_of_acne L2 - https://doi.org/10.1111/j.1365-2133.2005.06794.x DB - PRIME DP - Unbound Medicine ER -