Type your tag names separated by a space and hit enter

Being big or growing fast: systematic review of size and growth in infancy and later obesity.

Abstract

OBJECTIVES

To assess the association between infant size or growth and subsequent obesity and to determine if any association has been stable over time.

DESIGN

Systematic review.

DATA SOURCES

Medline, Embase, bibliographies of included studies, contact with first authors of included studies and other experts.

INCLUSION CRITERIA

Studies that assessed the relation between infant size or growth during the first two years of life and subsequent obesity.

MAIN OUTCOME MEASURE

Obesity at any age after infancy.

RESULTS

24 studies met the inclusion criteria (22 cohort and two case-control studies). Of these, 18 assessed the relation between infant size and subsequent obesity, most showing that infants who were defined as "obese" or who were at the highest end of the distribution for weight or body mass index were at increased risk of obesity. Compared with non-obese infants, in those who had been obese odds ratios or relative risks for subsequent obesity ranged from 1.35 to 9.38. Ten studies assessed the relation of infant growth with subsequent obesity and most showed that infants who grew more rapidly were at increased risk of obesity. Compared with other infants, in infants with rapid growth odds ratios and relative risks of later obesity ranged from 1.17 to 5.70. Associations were consistent for obesity at different ages and for people born over a period from 1927 to 1994.

CONCLUSIONS

Infants who are at the highest end of the distribution for weight or body mass index or who grow rapidly during infancy are at increased risk of subsequent obesity.

Links

  • PMC Free PDF
  • PMC Free Full Text
  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    MRC Epidemiology Resource Centre, University of Southampton, Southampton General Hospital, Southampton SO16 6YD. jb@mrc.soton.ac.uk

    , , , ,

    Source

    BMJ (Clinical research ed.) 331:7522 2005 Oct 22 pg 929

    MeSH

    Adolescent
    Adult
    Body Mass Index
    Body Weight
    Child
    Growth
    Humans
    Infant
    Obesity
    Risk Assessment

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't
    Review
    Systematic Review

    Language

    eng

    PubMed ID

    16227306

    Citation

    Baird, Janis, et al. "Being Big or Growing Fast: Systematic Review of Size and Growth in Infancy and Later Obesity." BMJ (Clinical Research Ed.), vol. 331, no. 7522, 2005, p. 929.
    Baird J, Fisher D, Lucas P, et al. Being big or growing fast: systematic review of size and growth in infancy and later obesity. BMJ. 2005;331(7522):929.
    Baird, J., Fisher, D., Lucas, P., Kleijnen, J., Roberts, H., & Law, C. (2005). Being big or growing fast: systematic review of size and growth in infancy and later obesity. BMJ (Clinical Research Ed.), 331(7522), p. 929.
    Baird J, et al. Being Big or Growing Fast: Systematic Review of Size and Growth in Infancy and Later Obesity. BMJ. 2005 Oct 22;331(7522):929. PubMed PMID: 16227306.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Being big or growing fast: systematic review of size and growth in infancy and later obesity. AU - Baird,Janis, AU - Fisher,David, AU - Lucas,Patricia, AU - Kleijnen,Jos, AU - Roberts,Helen, AU - Law,Catherine, Y1 - 2005/10/14/ PY - 2005/10/18/pubmed PY - 2005/11/15/medline PY - 2005/10/18/entrez SP - 929 EP - 929 JF - BMJ (Clinical research ed.) JO - BMJ VL - 331 IS - 7522 N2 - OBJECTIVES: To assess the association between infant size or growth and subsequent obesity and to determine if any association has been stable over time. DESIGN: Systematic review. DATA SOURCES: Medline, Embase, bibliographies of included studies, contact with first authors of included studies and other experts. INCLUSION CRITERIA: Studies that assessed the relation between infant size or growth during the first two years of life and subsequent obesity. MAIN OUTCOME MEASURE: Obesity at any age after infancy. RESULTS: 24 studies met the inclusion criteria (22 cohort and two case-control studies). Of these, 18 assessed the relation between infant size and subsequent obesity, most showing that infants who were defined as "obese" or who were at the highest end of the distribution for weight or body mass index were at increased risk of obesity. Compared with non-obese infants, in those who had been obese odds ratios or relative risks for subsequent obesity ranged from 1.35 to 9.38. Ten studies assessed the relation of infant growth with subsequent obesity and most showed that infants who grew more rapidly were at increased risk of obesity. Compared with other infants, in infants with rapid growth odds ratios and relative risks of later obesity ranged from 1.17 to 5.70. Associations were consistent for obesity at different ages and for people born over a period from 1927 to 1994. CONCLUSIONS: Infants who are at the highest end of the distribution for weight or body mass index or who grow rapidly during infancy are at increased risk of subsequent obesity. SN - 1756-1833 UR - https://www.unboundmedicine.com/medline/citation/16227306/full_citation L2 - http://www.bmj.com/cgi/pmidlookup?view=long&pmid=16227306 DB - PRIME DP - Unbound Medicine ER -