Tags

Type your tag names separated by a space and hit enter

REM sleep behavior disorder, hallucinations, and cognitive impairment in Parkinson's disease.
Mov Disord. 2006 Apr; 21(4):462-6.MD

Abstract

The objective of this study was to evaluate the relationship between REM sleep behavior disorder (RBD), hallucinations, and cognitive impairment in Parkinson's disease (PD). One hundred and ten PD patients, divided into three groups (without RBD or hallucinations; with RBD but no hallucinations; with RBD and hallucinations), were submitted to neuropsychological evaluation. The group without RBD and hallucinations showed normal neuropsychological tests when compared to normal controls. The group with hallucinations was characterized by a more severe cognitive impairment affecting both short- and long-term memory, logical abilities, and frontal functions, while the RBD-only group presented frontal impairment. The hypothesis that RBD in PD can be considered a risk factor not only of the hallucinations but also of more severe and diffuse cognitive abnormalities needs to be strengthened through a longitudinal evaluation.

Authors+Show Affiliations

Laboratory of Neuropsychology, IRCCS C. Mondino Institute of Neurology, Pavia, Italy. elena.sinforiani@mondino.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

16228998

Citation

Sinforiani, Elena, et al. "REM Sleep Behavior Disorder, Hallucinations, and Cognitive Impairment in Parkinson's Disease." Movement Disorders : Official Journal of the Movement Disorder Society, vol. 21, no. 4, 2006, pp. 462-6.
Sinforiani E, Zangaglia R, Manni R, et al. REM sleep behavior disorder, hallucinations, and cognitive impairment in Parkinson's disease. Mov Disord. 2006;21(4):462-6.
Sinforiani, E., Zangaglia, R., Manni, R., Cristina, S., Marchioni, E., Nappi, G., Mancini, F., & Pacchetti, C. (2006). REM sleep behavior disorder, hallucinations, and cognitive impairment in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society, 21(4), 462-6.
Sinforiani E, et al. REM Sleep Behavior Disorder, Hallucinations, and Cognitive Impairment in Parkinson's Disease. Mov Disord. 2006;21(4):462-6. PubMed PMID: 16228998.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - REM sleep behavior disorder, hallucinations, and cognitive impairment in Parkinson's disease. AU - Sinforiani,Elena, AU - Zangaglia,Roberta, AU - Manni,Raffaele, AU - Cristina,Silvano, AU - Marchioni,Enrico, AU - Nappi,Giuseppe, AU - Mancini,Francesca, AU - Pacchetti,Claudio, PY - 2005/10/18/pubmed PY - 2006/9/27/medline PY - 2005/10/18/entrez SP - 462 EP - 6 JF - Movement disorders : official journal of the Movement Disorder Society JO - Mov Disord VL - 21 IS - 4 N2 - The objective of this study was to evaluate the relationship between REM sleep behavior disorder (RBD), hallucinations, and cognitive impairment in Parkinson's disease (PD). One hundred and ten PD patients, divided into three groups (without RBD or hallucinations; with RBD but no hallucinations; with RBD and hallucinations), were submitted to neuropsychological evaluation. The group without RBD and hallucinations showed normal neuropsychological tests when compared to normal controls. The group with hallucinations was characterized by a more severe cognitive impairment affecting both short- and long-term memory, logical abilities, and frontal functions, while the RBD-only group presented frontal impairment. The hypothesis that RBD in PD can be considered a risk factor not only of the hallucinations but also of more severe and diffuse cognitive abnormalities needs to be strengthened through a longitudinal evaluation. SN - 0885-3185 UR - https://www.unboundmedicine.com/medline/citation/16228998/REM_sleep_behavior_disorder_hallucinations_and_cognitive_impairment_in_Parkinson's_disease_ L2 - https://doi.org/10.1002/mds.20719 DB - PRIME DP - Unbound Medicine ER -