Uncoupling proteins: targets of endocrine disruptors?Mol Cell Endocrinol. 2005 Dec 01; 244(1-2):79-86.MC
The roles of uncoupling proteins (UCPs) are discussed. Particular attention has been paid to the roles of UCP2 to UCP5 as agents mediating thermogenesis, and to the concept of limited or "mild" uncoupling as a means of reducing oxidative stress. The role of the endocrine system, thyroid hormones and catecholamines, in regulating expression of UCPs is also discussed.