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Twelve-year course and outcome predictors of anorexia nervosa.
Int J Eat Disord. 2006 Mar; 39(2):87-100.IJ

Abstract

OBJECTIVE

The current study presents the long-term course of anorexia nervosa (AN) over 12 years in a large sample of 103 patients diagnosed according to criteria in the 4th ed. of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV).

METHOD

Assessments were made at the beginning of therapy, at the end of therapy, at the 2-year follow-up, at the 6-year follow-up, and at the 12-year follow-up. Self-rating and an expert-rating interview data were obtained.

RESULTS

The participation rate at the 12-year follow-up was 88% of those alive. There was substantial improvement during therapy, a moderate (in many instances nonsignificant) decline during the first 2 years posttreatment, and further improvement from 3 to 12 years posttreatment. Based on a global 12-year outcome score, 27.5% had a good outcome, 25.3% an intermediate outcome, 39.6% had a poor outcome, and 7 (7.7%) were deceased. At the 12-year follow-up 19.0% had AN, 9.5% had bulimia nervosa-purging type (BN-P), 19.0% were classified as eating disorder not otherwise specified (EDNOS). A total of 52.4% showed no major DSM-IV eating disorder and 0% had binge eating disorder (BED). Systematic-strictly empirically based-model building resulted in a parsimonious model including four predictors of unfavorable 12-year outcome explaining 45% of the variance, that is, sexual problems, impulsivity, long duration of inpatient treatment, and long duration of an eating disorder.

CONCLUSION

Mortality was high and symptomatic recovery protracted. Impulsivity, symptom severity, and chronicity were the important factors for predicting the 12-year outcome.

Authors+Show Affiliations

Department of Psychiatry, University of Munich, Munich, Germany. MFichter@Schoen-Klinken.deNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16231345

Citation

Fichter, Manfred M., et al. "Twelve-year Course and Outcome Predictors of Anorexia Nervosa." The International Journal of Eating Disorders, vol. 39, no. 2, 2006, pp. 87-100.
Fichter MM, Quadflieg N, Hedlund S. Twelve-year course and outcome predictors of anorexia nervosa. Int J Eat Disord. 2006;39(2):87-100.
Fichter, M. M., Quadflieg, N., & Hedlund, S. (2006). Twelve-year course and outcome predictors of anorexia nervosa. The International Journal of Eating Disorders, 39(2), 87-100.
Fichter MM, Quadflieg N, Hedlund S. Twelve-year Course and Outcome Predictors of Anorexia Nervosa. Int J Eat Disord. 2006;39(2):87-100. PubMed PMID: 16231345.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Twelve-year course and outcome predictors of anorexia nervosa. AU - Fichter,Manfred M, AU - Quadflieg,Norbert, AU - Hedlund,Susanne, PY - 2005/10/19/pubmed PY - 2006/6/13/medline PY - 2005/10/19/entrez SP - 87 EP - 100 JF - The International journal of eating disorders JO - Int J Eat Disord VL - 39 IS - 2 N2 - OBJECTIVE: The current study presents the long-term course of anorexia nervosa (AN) over 12 years in a large sample of 103 patients diagnosed according to criteria in the 4th ed. of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV). METHOD: Assessments were made at the beginning of therapy, at the end of therapy, at the 2-year follow-up, at the 6-year follow-up, and at the 12-year follow-up. Self-rating and an expert-rating interview data were obtained. RESULTS: The participation rate at the 12-year follow-up was 88% of those alive. There was substantial improvement during therapy, a moderate (in many instances nonsignificant) decline during the first 2 years posttreatment, and further improvement from 3 to 12 years posttreatment. Based on a global 12-year outcome score, 27.5% had a good outcome, 25.3% an intermediate outcome, 39.6% had a poor outcome, and 7 (7.7%) were deceased. At the 12-year follow-up 19.0% had AN, 9.5% had bulimia nervosa-purging type (BN-P), 19.0% were classified as eating disorder not otherwise specified (EDNOS). A total of 52.4% showed no major DSM-IV eating disorder and 0% had binge eating disorder (BED). Systematic-strictly empirically based-model building resulted in a parsimonious model including four predictors of unfavorable 12-year outcome explaining 45% of the variance, that is, sexual problems, impulsivity, long duration of inpatient treatment, and long duration of an eating disorder. CONCLUSION: Mortality was high and symptomatic recovery protracted. Impulsivity, symptom severity, and chronicity were the important factors for predicting the 12-year outcome. SN - 0276-3478 UR - https://www.unboundmedicine.com/medline/citation/16231345/Twelve_year_course_and_outcome_predictors_of_anorexia_nervosa_ L2 - https://doi.org/10.1002/eat.20215 DB - PRIME DP - Unbound Medicine ER -