Tags

Type your tag names separated by a space and hit enter

Obesity and incidence of cancer: a large cohort study of over 145,000 adults in Austria.
Br J Cancer. 2005 Oct 31; 93(9):1062-7.BJ

Abstract

We investigated the relation of overweight and obesity with cancer in a population-based cohort of more than 145 000 Austrian adults over an average of 9.9 years. Incident cancers (n=6241) were identified through the state cancer registry. Using Cox proportional-hazards models adjusted for smoking and occupation, increases in relative body weight in men were associated with colon cancer (hazard rate (HR) ratio 2.48; 95% confidence interval (CI): 1.15, 5.39 for body mass index (BMI) > or =35 kg m(-2)) and pancreatic cancer (HR 2.34, 95% CI: 1.17, 4.66 for BMI>30 kg m(-2)) compared to participants with normal weight (BMI 18.5-24.9 kg m(-2)). In women, there was a weak positive association between increasing BMI and all cancers combined, and strong associations with non-Hodgkin's lymphomas (HR 2.86, 95% CI: 1.49, 5.49 for BMI> or =30 kg m(-2)) and cancers of the uterine corpus (HR 3.93, 95% CI: 2.35, 6.56 for BMI> or =35 kg m(-2)). Incidence of breast cancer was positively associated with high BMI only after age 65 years. These findings provide further evidence that overweight is associated with the incidence of several types of cancer.

Authors+Show Affiliations

Department of Epidemiology, University of Ulm, Helmholtzstrasse 22, 89081 Ulm, Germany. kilian.rapp@medizin.uni-ulm.deNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

16234822

Citation

Rapp, K, et al. "Obesity and Incidence of Cancer: a Large Cohort Study of Over 145,000 Adults in Austria." British Journal of Cancer, vol. 93, no. 9, 2005, pp. 1062-7.
Rapp K, Schroeder J, Klenk J, et al. Obesity and incidence of cancer: a large cohort study of over 145,000 adults in Austria. Br J Cancer. 2005;93(9):1062-7.
Rapp, K., Schroeder, J., Klenk, J., Stoehr, S., Ulmer, H., Concin, H., Diem, G., Oberaigner, W., & Weiland, S. K. (2005). Obesity and incidence of cancer: a large cohort study of over 145,000 adults in Austria. British Journal of Cancer, 93(9), 1062-7.
Rapp K, et al. Obesity and Incidence of Cancer: a Large Cohort Study of Over 145,000 Adults in Austria. Br J Cancer. 2005 Oct 31;93(9):1062-7. PubMed PMID: 16234822.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Obesity and incidence of cancer: a large cohort study of over 145,000 adults in Austria. AU - Rapp,K, AU - Schroeder,J, AU - Klenk,J, AU - Stoehr,S, AU - Ulmer,H, AU - Concin,H, AU - Diem,G, AU - Oberaigner,W, AU - Weiland,S K, PY - 2005/10/20/pubmed PY - 2005/12/15/medline PY - 2005/10/20/entrez SP - 1062 EP - 7 JF - British journal of cancer JO - Br. J. Cancer VL - 93 IS - 9 N2 - We investigated the relation of overweight and obesity with cancer in a population-based cohort of more than 145 000 Austrian adults over an average of 9.9 years. Incident cancers (n=6241) were identified through the state cancer registry. Using Cox proportional-hazards models adjusted for smoking and occupation, increases in relative body weight in men were associated with colon cancer (hazard rate (HR) ratio 2.48; 95% confidence interval (CI): 1.15, 5.39 for body mass index (BMI) > or =35 kg m(-2)) and pancreatic cancer (HR 2.34, 95% CI: 1.17, 4.66 for BMI>30 kg m(-2)) compared to participants with normal weight (BMI 18.5-24.9 kg m(-2)). In women, there was a weak positive association between increasing BMI and all cancers combined, and strong associations with non-Hodgkin's lymphomas (HR 2.86, 95% CI: 1.49, 5.49 for BMI> or =30 kg m(-2)) and cancers of the uterine corpus (HR 3.93, 95% CI: 2.35, 6.56 for BMI> or =35 kg m(-2)). Incidence of breast cancer was positively associated with high BMI only after age 65 years. These findings provide further evidence that overweight is associated with the incidence of several types of cancer. SN - 0007-0920 UR - https://www.unboundmedicine.com/medline/citation/16234822/Obesity_and_incidence_of_cancer:_a_large_cohort_study_of_over_145000_adults_in_Austria_ L2 - http://dx.doi.org/10.1038/sj.bjc.6602819 DB - PRIME DP - Unbound Medicine ER -