Enantioselective construction of quaternary carbon centers by catalytic [2 + 2 + 2] cycloaddition of 1,6-enynes and alkynes.
Org Lett. 2005 Oct 27; 7(22):4955-7.OL

Abstract

[reaction: see text] The enantioselective [2 + 2 + 2] cycloaddition of 1,6-enynes and alkynes using chiral rhodium catalysts gave cycloadducts containing quaternary carbon stereocenters. Both symmetrical and unsymmetrical alkynes and acetylene could be used as coupling partners, and the corresponding bicyclic cyclohexa-1,3-dienes were obtained in good to excellent ee.

Authors+Show Affiliations

Shibata T

Department of Chemistry, School of Science and Engineering, Waseda University, Shinjuku, Tokyo, Japan. tshibata@waseda.jp

Arai Y

No affiliation info available

Tahara YK

No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16235931

Citation

Shibata, Takanori, et al. "Enantioselective Construction of Quaternary Carbon Centers By Catalytic [2 + 2 + 2] Cycloaddition of 1,6-enynes and Alkynes." Organic Letters, vol. 7, no. 22, 2005, pp. 4955-7.

Shibata T, Arai Y, Tahara YK. Enantioselective construction of quaternary carbon centers by catalytic [2 + 2 + 2] cycloaddition of 1,6-enynes and alkynes. Org Lett. 2005;7(22):4955-7.

Shibata, T., Arai, Y., & Tahara, Y. K. (2005). Enantioselective construction of quaternary carbon centers by catalytic [2 + 2 + 2] cycloaddition of 1,6-enynes and alkynes. Organic Letters, 7(22), 4955-7.

Shibata T, Arai Y, Tahara YK. Enantioselective Construction of Quaternary Carbon Centers By Catalytic [2 + 2 + 2] Cycloaddition of 1,6-enynes and Alkynes. Org Lett. 2005 Oct 27;7(22):4955-7. PubMed PMID: 16235931.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - Enantioselective construction of quaternary carbon centers by catalytic [2 + 2 + 2] cycloaddition of 1,6-enynes and alkynes. AU - Shibata,Takanori, AU - Arai,Yoshikazu, AU - Tahara,Yu-Ki, PY - 2005/10/21/pubmed PY - 2005/10/21/medline PY - 2005/10/21/entrez SP - 4955 EP - 7 JF - Organic letters JO - Org Lett VL - 7 IS - 22 N2 - [reaction: see text] The enantioselective [2 + 2 + 2] cycloaddition of 1,6-enynes and alkynes using chiral rhodium catalysts gave cycloadducts containing quaternary carbon stereocenters. Both symmetrical and unsymmetrical alkynes and acetylene could be used as coupling partners, and the corresponding bicyclic cyclohexa-1,3-dienes were obtained in good to excellent ee. SN - 1523-7060 UR - https://www.unboundmedicine.com/medline/citation/16235931/Enantioselective_construction_of_quaternary_carbon_centers_by_catalytic_[2_+_2_+_2]_cycloaddition_of_16_enynes_and_alkynes_ DB - PRIME DP - Unbound Medicine ER -

Tags

Enantioselective construction of quaternary carbon centers by catalytic [2 + 2 + 2] cycloaddition of 1,6-enynes and alkynes.Org Lett. 2005 Oct 27; 7(22):4955-7.OL