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Local anaesthetic flush reduces postoperative pain and haematoma formation after great saphenous vein stripping--a randomised controlled trial.
Eur J Vasc Endovasc Surg. 2006 Mar; 31(3):325-31.EJ

Abstract

OBJECTIVES

To observe the effect of local anaesthetic flush through the great saphenous vein (GSV) tunnel on postoperative pain and haematoma formation following saphenous vein stripping operations.

DESIGN

Prospective, double-blind, randomised, control trial.

METHODS

One hundred patients were randomized to receive 20 ml of local anaesthetic (bupivacaine 0.25% + adrenaline) or saline control flush through the GSV tunnel after stripping in a double-blind study. Visual analogue pain scores were used to measure postoperative pain daily for the 1st week, then at 3 weeks and 6 weeks. Patients were examined during the 1st, 3rd and 6th week for haematoma formation.

RESULTS

In the control group the median postoperative pain score was 4 (range 0-7) in the immediate postoperative period compared to a median of 1 (range 0-4) in the LA group (p<0.001). The median pain score on day-4 was 4 (range 1-6) (control) vs. 1 (range 0-3) (LA group) (p<0.001, Mann-Whitney Utest) and on day-6 it was 1 (range 0-5) (control) vs. 0 (range 0-5) (LA group) (p<0.001, Mann-Whitney). Twelve patients (24%) developed a haematoma in the GSV tunnel in the control group compared to three patients (6%) in the LA group (p = 0.007).

CONCLUSION

Flushing of the GSV tunnel with bupivacaine plus adrenaline significantly reduces postoperative pain and haematoma formation in patients undergoing GSV stripping for varicose veins.

Authors+Show Affiliations

Department of Vascular Surgery, Mid-Western Regional and St John's Hospitals, Limerick, Ireland. aamnis@aol.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

16236532

Citation

Nisar, A, et al. "Local Anaesthetic Flush Reduces Postoperative Pain and Haematoma Formation After Great Saphenous Vein Stripping--a Randomised Controlled Trial." European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery, vol. 31, no. 3, 2006, pp. 325-31.
Nisar A, Shabbir J, Tubassam MA, et al. Local anaesthetic flush reduces postoperative pain and haematoma formation after great saphenous vein stripping--a randomised controlled trial. Eur J Vasc Endovasc Surg. 2006;31(3):325-31.
Nisar, A., Shabbir, J., Tubassam, M. A., Shah, A. R., Khawaja, N., Kavanagh, E. G., Grace, P. A., & Burke, P. E. (2006). Local anaesthetic flush reduces postoperative pain and haematoma formation after great saphenous vein stripping--a randomised controlled trial. European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery, 31(3), 325-31.
Nisar A, et al. Local Anaesthetic Flush Reduces Postoperative Pain and Haematoma Formation After Great Saphenous Vein Stripping--a Randomised Controlled Trial. Eur J Vasc Endovasc Surg. 2006;31(3):325-31. PubMed PMID: 16236532.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Local anaesthetic flush reduces postoperative pain and haematoma formation after great saphenous vein stripping--a randomised controlled trial. AU - Nisar,A, AU - Shabbir,J, AU - Tubassam,M A, AU - Shah,A R, AU - Khawaja,N, AU - Kavanagh,E G, AU - Grace,P A, AU - Burke,P E, Y1 - 2005/10/19/ PY - 2005/02/26/received PY - 2005/08/14/accepted PY - 2005/10/21/pubmed PY - 2006/4/28/medline PY - 2005/10/21/entrez SP - 325 EP - 31 JF - European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery JO - Eur J Vasc Endovasc Surg VL - 31 IS - 3 N2 - OBJECTIVES: To observe the effect of local anaesthetic flush through the great saphenous vein (GSV) tunnel on postoperative pain and haematoma formation following saphenous vein stripping operations. DESIGN: Prospective, double-blind, randomised, control trial. METHODS: One hundred patients were randomized to receive 20 ml of local anaesthetic (bupivacaine 0.25% + adrenaline) or saline control flush through the GSV tunnel after stripping in a double-blind study. Visual analogue pain scores were used to measure postoperative pain daily for the 1st week, then at 3 weeks and 6 weeks. Patients were examined during the 1st, 3rd and 6th week for haematoma formation. RESULTS: In the control group the median postoperative pain score was 4 (range 0-7) in the immediate postoperative period compared to a median of 1 (range 0-4) in the LA group (p<0.001). The median pain score on day-4 was 4 (range 1-6) (control) vs. 1 (range 0-3) (LA group) (p<0.001, Mann-Whitney Utest) and on day-6 it was 1 (range 0-5) (control) vs. 0 (range 0-5) (LA group) (p<0.001, Mann-Whitney). Twelve patients (24%) developed a haematoma in the GSV tunnel in the control group compared to three patients (6%) in the LA group (p = 0.007). CONCLUSION: Flushing of the GSV tunnel with bupivacaine plus adrenaline significantly reduces postoperative pain and haematoma formation in patients undergoing GSV stripping for varicose veins. SN - 1078-5884 UR - https://www.unboundmedicine.com/medline/citation/16236532/Local_anaesthetic_flush_reduces_postoperative_pain_and_haematoma_formation_after_great_saphenous_vein_stripping__a_randomised_controlled_trial_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1078-5884(05)00511-3 DB - PRIME DP - Unbound Medicine ER -