Tags

Type your tag names separated by a space and hit enter

Use of antiviral agents and other measures in an influenza pandemic.
Neth J Med. 2005 Oct; 63(9):339-43.NJ

Abstract

The Dutch Ministry of Health asked the Health Council for advice on how to prepare for a possible influenza pandemic. In two advisory reports the Committee responsible indicated the measures that it believes would need to be taken if such a pandemic were to reach the Netherlands. During a pandemic, the Committee recommends that every resident of the Netherlands with influenza-like illness should be treated with neuraminidase inhibitors such as antiviral agents. This approach serves to mitigate the course of the disease, to reduce infectivity and to allow patients to build up immunity to the virus. Since up to 30% of the population could become ill, the Committee anticipates that a stock of five million courses of the neuraminidase inhibitor oseltamivir is sufficient. If a pandemic were to occur at a time that the stock does not exceed the present 225,000 courses, the committee advises restricting treatment to three specified groups of patients. If the first few patients are traced shortly after they fall ill, the Committee recommends treatment of the patient and postexposure prophylaxis for his/her close contacts. The Committee does not advocate prophylaxis in general, but it can envisage prophylaxis for particular groups of patients or under particular circumstances. The Committee believes that in order to reduce rapid spread of the virus, schools should be closed and events where large numbers of people gather in a confined space should be cancelled. Because this recommendation would have major social and economic consequences, the Committee understands that its implication will depend on the anticipated severity and extent of the pandemic. The Committee regards vaccination against influenza as the best means of protecting the population. The development of a vaccine should be the absolute priority.

Authors+Show Affiliations

Health Council of the Netherlands, PO Box 16052, 2500 BB The Hague, the Netherlands. k.groeneveld@gr.nlNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16244380

Citation

Groeneveld, K, and J van der Noordaa. "Use of Antiviral Agents and Other Measures in an Influenza Pandemic." The Netherlands Journal of Medicine, vol. 63, no. 9, 2005, pp. 339-43.
Groeneveld K, van der Noordaa J. Use of antiviral agents and other measures in an influenza pandemic. Neth J Med. 2005;63(9):339-43.
Groeneveld, K., & van der Noordaa, J. (2005). Use of antiviral agents and other measures in an influenza pandemic. The Netherlands Journal of Medicine, 63(9), 339-43.
Groeneveld K, van der Noordaa J. Use of Antiviral Agents and Other Measures in an Influenza Pandemic. Neth J Med. 2005;63(9):339-43. PubMed PMID: 16244380.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Use of antiviral agents and other measures in an influenza pandemic. AU - Groeneveld,K, AU - van der Noordaa,J, PY - 2005/10/26/pubmed PY - 2005/12/13/medline PY - 2005/10/26/entrez SP - 339 EP - 43 JF - The Netherlands journal of medicine JO - Neth J Med VL - 63 IS - 9 N2 - The Dutch Ministry of Health asked the Health Council for advice on how to prepare for a possible influenza pandemic. In two advisory reports the Committee responsible indicated the measures that it believes would need to be taken if such a pandemic were to reach the Netherlands. During a pandemic, the Committee recommends that every resident of the Netherlands with influenza-like illness should be treated with neuraminidase inhibitors such as antiviral agents. This approach serves to mitigate the course of the disease, to reduce infectivity and to allow patients to build up immunity to the virus. Since up to 30% of the population could become ill, the Committee anticipates that a stock of five million courses of the neuraminidase inhibitor oseltamivir is sufficient. If a pandemic were to occur at a time that the stock does not exceed the present 225,000 courses, the committee advises restricting treatment to three specified groups of patients. If the first few patients are traced shortly after they fall ill, the Committee recommends treatment of the patient and postexposure prophylaxis for his/her close contacts. The Committee does not advocate prophylaxis in general, but it can envisage prophylaxis for particular groups of patients or under particular circumstances. The Committee believes that in order to reduce rapid spread of the virus, schools should be closed and events where large numbers of people gather in a confined space should be cancelled. Because this recommendation would have major social and economic consequences, the Committee understands that its implication will depend on the anticipated severity and extent of the pandemic. The Committee regards vaccination against influenza as the best means of protecting the population. The development of a vaccine should be the absolute priority. SN - 0300-2977 UR - https://www.unboundmedicine.com/medline/citation/16244380/Use_of_antiviral_agents_and_other_measures_in_an_influenza_pandemic_ L2 - http://www.njmonline.nl/njm/getarticle.php?v=63&i=9&p=339 DB - PRIME DP - Unbound Medicine ER -