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Clinical features of chronic pancreatitis in Korea: a multicenter nationwide study.
Digestion 2005; 72(4):207-11D

Abstract

BACKGROUND/AIMS

No reliable nationwide clinical data about chronic pancreatitis (CP) was available in Korea. The etiology and clinical features of CP were investigated using a multicenter nationwide study.

METHODS

814 cases of CP were enrolled retrospectively over the past 4 years at 13 hospitals. The following data were obtained from all patients: etiology, symptoms, complications, and surgery.

RESULT

Alcohol (64.3%) was the major cause of CP and idiopathic CP (20.8%) was the second most common form. Mean patient age was 50.6 years and the male:female ratio was 6:1 (24:1 for alcoholic CP vs. 2:1 in idiopathic CP, p < 0.001). Diabetes (31.6%), pseudocysts (28.4%), biliary stricture (13.9%), and pancreatic ascites (6.6%) were the main complications. Of these, diabetes (35 vs. 26%) and pseudocyst (33.7 vs. 21.9%) were more frequent in alcoholic than in idiopathic CP. Pancreatic cancer developed in 25 patients (3.1%) during follow-up and their mean age was 59.1 years.

CONCLUSIONS

In Korea, alcohol is the most common etiology of CP. Moreover, diabetes and pseudocysts are frequent complications, especially in alcoholic CP, and pancreatic cancer development is not infrequent.

Authors+Show Affiliations

Korean Multicenter Study Group on Chronic Pancreatitis, Division of Gastroenterology, Department of Internal Medicine, Seoul National University College of Medicine, 28 Yungon-dong, Chongno-gu, Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16260866

Citation

Ryu, Ji Kon, et al. "Clinical Features of Chronic Pancreatitis in Korea: a Multicenter Nationwide Study." Digestion, vol. 72, no. 4, 2005, pp. 207-11.
Ryu JK, Lee JK, Kim YT, et al. Clinical features of chronic pancreatitis in Korea: a multicenter nationwide study. Digestion. 2005;72(4):207-11.
Ryu, J. K., Lee, J. K., Kim, Y. T., Lee, D. K., Seo, D. W., Lee, K. T., ... Yoon, Y. B. (2005). Clinical features of chronic pancreatitis in Korea: a multicenter nationwide study. Digestion, 72(4), pp. 207-11.
Ryu JK, et al. Clinical Features of Chronic Pancreatitis in Korea: a Multicenter Nationwide Study. Digestion. 2005;72(4):207-11. PubMed PMID: 16260866.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical features of chronic pancreatitis in Korea: a multicenter nationwide study. AU - Ryu,Ji Kon, AU - Lee,Jun Kyu, AU - Kim,Yong-Tae, AU - Lee,Dong Ki, AU - Seo,Dong Wan, AU - Lee,Kyu Taek, AU - Kim,Ho Gak, AU - Kim,Jae Seon, AU - Lee,Hong Sik, AU - Kim,Tae Nyeun, AU - Rho,Myung Hwan, AU - Moon,Jong Ho, AU - Lee,Jin, AU - Choi,Ho-Soon, AU - Lee,Woo Jin, AU - Yoo,Byung Moo, AU - Yoon,Yong Bum, AU - ,, Y1 - 2005/10/09/ PY - 2005/07/08/received PY - 2005/09/09/accepted PY - 2005/11/2/pubmed PY - 2006/2/24/medline PY - 2005/11/2/entrez SP - 207 EP - 11 JF - Digestion JO - Digestion VL - 72 IS - 4 N2 - BACKGROUND/AIMS: No reliable nationwide clinical data about chronic pancreatitis (CP) was available in Korea. The etiology and clinical features of CP were investigated using a multicenter nationwide study. METHODS: 814 cases of CP were enrolled retrospectively over the past 4 years at 13 hospitals. The following data were obtained from all patients: etiology, symptoms, complications, and surgery. RESULT: Alcohol (64.3%) was the major cause of CP and idiopathic CP (20.8%) was the second most common form. Mean patient age was 50.6 years and the male:female ratio was 6:1 (24:1 for alcoholic CP vs. 2:1 in idiopathic CP, p < 0.001). Diabetes (31.6%), pseudocysts (28.4%), biliary stricture (13.9%), and pancreatic ascites (6.6%) were the main complications. Of these, diabetes (35 vs. 26%) and pseudocyst (33.7 vs. 21.9%) were more frequent in alcoholic than in idiopathic CP. Pancreatic cancer developed in 25 patients (3.1%) during follow-up and their mean age was 59.1 years. CONCLUSIONS: In Korea, alcohol is the most common etiology of CP. Moreover, diabetes and pseudocysts are frequent complications, especially in alcoholic CP, and pancreatic cancer development is not infrequent. SN - 0012-2823 UR - https://www.unboundmedicine.com/medline/citation/16260866/Clinical_features_of_chronic_pancreatitis_in_Korea:_a_multicenter_nationwide_study_ L2 - https://www.karger.com?DOI=10.1159/000089414 DB - PRIME DP - Unbound Medicine ER -