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Allergy to mammal's meat in adult life: immunologic and follow-up study.
J Investig Allergol Clin Immunol. 2005; 15(3):228-31.JI

Abstract

Allergy to bovine meat and Bovine serum albumin (BSA) is exceptional, especially in the adult life. BSA is considered a minor allergen in cow's milk allergy, but there is little information about this antigen in reactions produced by other beef products as meat. To our knowledge, evolutive studies of beef's allergic patients have not been reported.

OBJECTIVE

To present one patient with several allergic reactions (urticaria-angioedema) after eating different mammals' meat.

METHODS

The patient underwent allergy testing through skin prick test (SPT), specific IgE detection and SDS-PAGE Immunoblotting and Immunodot inhibition studies. Periodic determinations of specific IgE to meats and epithelia were performed.

RESULTS

Routine studies for chronic urticaria were normal or negative. SPT showed positive responses to pork, cow, rabbit and lamb meat, and dog, pork, sheep and cow epithelia. It was negative to cat, horse, guinea pig, rabbit, lamb, mouse epithelia, mixture of feathers, cow milk, soybean, mustard, mites and chicken meat and Anisakis simplex. Intradermal testing to BSA was positive. Determinations of specific IgE were positive to beef meat, lamb meat, pork meat and rabbit meat, dog, cat, cow, sheep and pork dander, cow's milk, and negative to chicken meat. Immunoblot and immunodot studies showed IgE recognition bands to bovine and lamb meat which were totally inhibited by BSA. A progressive reduction of the total and specific IgE, the latter until its total negativization, has been observed in the following three-year period.

CONCLUSION

We report a case of IgE-mediated urticaria-angioedema due to BSA hypersensitivity, possibly induced by a subclinical sensitivity to dog and cat epithelium. The exclusion diet in patients allergic to these foods may be a progressive loss of clinical allergy.

Authors+Show Affiliations

victoriafuente@terra.esNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

16261963

Citation

Fuentes Aparicio, V, et al. "Allergy to Mammal's Meat in Adult Life: Immunologic and Follow-up Study." Journal of Investigational Allergology & Clinical Immunology, vol. 15, no. 3, 2005, pp. 228-31.
Fuentes Aparicio V, Sánchez Marcén I, Pérez Montero A, et al. Allergy to mammal's meat in adult life: immunologic and follow-up study. J Investig Allergol Clin Immunol. 2005;15(3):228-31.
Fuentes Aparicio, V., Sánchez Marcén, I., Pérez Montero, A., Baeza, M. L., & de Barrio Fernández, M. (2005). Allergy to mammal's meat in adult life: immunologic and follow-up study. Journal of Investigational Allergology & Clinical Immunology, 15(3), 228-31.
Fuentes Aparicio V, et al. Allergy to Mammal's Meat in Adult Life: Immunologic and Follow-up Study. J Investig Allergol Clin Immunol. 2005;15(3):228-31. PubMed PMID: 16261963.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Allergy to mammal's meat in adult life: immunologic and follow-up study. AU - Fuentes Aparicio,V, AU - Sánchez Marcén,I, AU - Pérez Montero,A, AU - Baeza,M L, AU - de Barrio Fernández,M, PY - 2005/11/3/pubmed PY - 2006/5/11/medline PY - 2005/11/3/entrez SP - 228 EP - 31 JF - Journal of investigational allergology & clinical immunology JO - J Investig Allergol Clin Immunol VL - 15 IS - 3 N2 - UNLABELLED: Allergy to bovine meat and Bovine serum albumin (BSA) is exceptional, especially in the adult life. BSA is considered a minor allergen in cow's milk allergy, but there is little information about this antigen in reactions produced by other beef products as meat. To our knowledge, evolutive studies of beef's allergic patients have not been reported. OBJECTIVE: To present one patient with several allergic reactions (urticaria-angioedema) after eating different mammals' meat. METHODS: The patient underwent allergy testing through skin prick test (SPT), specific IgE detection and SDS-PAGE Immunoblotting and Immunodot inhibition studies. Periodic determinations of specific IgE to meats and epithelia were performed. RESULTS: Routine studies for chronic urticaria were normal or negative. SPT showed positive responses to pork, cow, rabbit and lamb meat, and dog, pork, sheep and cow epithelia. It was negative to cat, horse, guinea pig, rabbit, lamb, mouse epithelia, mixture of feathers, cow milk, soybean, mustard, mites and chicken meat and Anisakis simplex. Intradermal testing to BSA was positive. Determinations of specific IgE were positive to beef meat, lamb meat, pork meat and rabbit meat, dog, cat, cow, sheep and pork dander, cow's milk, and negative to chicken meat. Immunoblot and immunodot studies showed IgE recognition bands to bovine and lamb meat which were totally inhibited by BSA. A progressive reduction of the total and specific IgE, the latter until its total negativization, has been observed in the following three-year period. CONCLUSION: We report a case of IgE-mediated urticaria-angioedema due to BSA hypersensitivity, possibly induced by a subclinical sensitivity to dog and cat epithelium. The exclusion diet in patients allergic to these foods may be a progressive loss of clinical allergy. SN - 1018-9068 UR - https://www.unboundmedicine.com/medline/citation/16261963/Allergy_to_mammal's_meat_in_adult_life:_immunologic_and_follow_up_study_ L2 - https://medlineplus.gov/foodallergy.html DB - PRIME DP - Unbound Medicine ER -