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Synthesis of isoxazoles via electrophilic cyclization.
Org Lett. 2005 Nov 10; 7(23):5203-5.OL

Abstract

[reaction: see text] A variety of 3,5-disubstituted 4-halo(seleno)isoxazoles are readily prepared in good to excellent yields under mild reaction conditions by the reaction of 2-alkyn-1-one O-methyl oximes with ICl, I2, Br2, or PhSeBr.

Authors+Show Affiliations

Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA.No affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

16268538

Citation

Waldo, Jesse P., and Richard C. Larock. "Synthesis of Isoxazoles Via Electrophilic Cyclization." Organic Letters, vol. 7, no. 23, 2005, pp. 5203-5.
Waldo JP, Larock RC. Synthesis of isoxazoles via electrophilic cyclization. Org Lett. 2005;7(23):5203-5.
Waldo, J. P., & Larock, R. C. (2005). Synthesis of isoxazoles via electrophilic cyclization. Organic Letters, 7(23), 5203-5.
Waldo JP, Larock RC. Synthesis of Isoxazoles Via Electrophilic Cyclization. Org Lett. 2005 Nov 10;7(23):5203-5. PubMed PMID: 16268538.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Synthesis of isoxazoles via electrophilic cyclization. AU - Waldo,Jesse P, AU - Larock,Richard C, PY - 2005/11/5/pubmed PY - 2006/8/10/medline PY - 2005/11/5/entrez SP - 5203 EP - 5 JF - Organic letters JO - Org Lett VL - 7 IS - 23 N2 - [reaction: see text] A variety of 3,5-disubstituted 4-halo(seleno)isoxazoles are readily prepared in good to excellent yields under mild reaction conditions by the reaction of 2-alkyn-1-one O-methyl oximes with ICl, I2, Br2, or PhSeBr. SN - 1523-7060 UR - https://www.unboundmedicine.com/medline/citation/16268538/Synthesis_of_isoxazoles_via_electrophilic_cyclization_ DB - PRIME DP - Unbound Medicine ER -