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Efficient rhodium-catalyzed asymmetric hydrogenation for the synthesis of a new class of N-aryl beta-amino acid derivatives.
Org Lett. 2005 Nov 10; 7(23):5343-5.OL

Abstract

[reaction: see text] N-Aryl beta-amino esters were obtained by asymmetric hydrogenation of a new class of N-aryl beta-enamino esters. High conversions and up to 96.3% ee values were achieved with a Rh-TangPhos catalyst.

Authors+Show Affiliations

Dai Q
Department of Chemistry, The Pennsylvania State University, 104 Chemistry Building, University Park, Pennsylvania 16802, USA.
Yang W
No affiliation info available
Zhang X
No affiliation info available

MeSH

Amino AcidsCatalysisHydrogenationIndicators and ReagentsMolecular StructureRhodiumStereoisomerism

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

16268574

Citation

Dai, Qian, et al. "Efficient Rhodium-catalyzed Asymmetric Hydrogenation for the Synthesis of a New Class of N-aryl Beta-amino Acid Derivatives." Organic Letters, vol. 7, no. 23, 2005, pp. 5343-5.
Dai Q, Yang W, Zhang X. Efficient rhodium-catalyzed asymmetric hydrogenation for the synthesis of a new class of N-aryl beta-amino acid derivatives. Org Lett. 2005;7(23):5343-5.
Dai, Q., Yang, W., & Zhang, X. (2005). Efficient rhodium-catalyzed asymmetric hydrogenation for the synthesis of a new class of N-aryl beta-amino acid derivatives. Organic Letters, 7(23), 5343-5.
Dai Q, Yang W, Zhang X. Efficient Rhodium-catalyzed Asymmetric Hydrogenation for the Synthesis of a New Class of N-aryl Beta-amino Acid Derivatives. Org Lett. 2005 Nov 10;7(23):5343-5. PubMed PMID: 16268574.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Efficient rhodium-catalyzed asymmetric hydrogenation for the synthesis of a new class of N-aryl beta-amino acid derivatives. AU - Dai,Qian, AU - Yang,Weiran, AU - Zhang,Xumu, PY - 2005/11/5/pubmed PY - 2006/8/10/medline PY - 2005/11/5/entrez SP - 5343 EP - 5 JF - Organic letters JO - Org Lett VL - 7 IS - 23 N2 - [reaction: see text] N-Aryl beta-amino esters were obtained by asymmetric hydrogenation of a new class of N-aryl beta-enamino esters. High conversions and up to 96.3% ee values were achieved with a Rh-TangPhos catalyst. SN - 1523-7060 UR - https://www.unboundmedicine.com/medline/citation/16268574/Efficient_rhodium_catalyzed_asymmetric_hydrogenation_for_the_synthesis_of_a_new_class_of_N_aryl_beta_amino_acid_derivatives_ DB - PRIME DP - Unbound Medicine ER -