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The genesis of a pandemic influenza virus.

Abstract

Pandemic influenza viruses pose a significant threat to public health worldwide. In a recent Nature paper, Taubenberger et al. (2005) now report remarkable similarities between the polymerase genes of the influenza virus that caused the 1918 Spanish influenza pandemic and those of avian influenza viruses. Meanwhile, Tumpey et al. (2005) reporting in Science show that the reconstructed 1918 Spanish influenza virus kills mice faster than any other influenza virus so far tested.

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    Authors+Show Affiliations

    Russell CJ
    ,

    Department of Infectious Diseases, St.Jude Children's Hospital, Memphis, Tennessee 38105, USA.

    Webster RG

    Source

    Cell 123:3 2005 Nov 04 pg 368-71

    MeSH

    Animals
    Birds
    Disease Outbreaks
    Hemagglutinin Glycoproteins, Influenza Virus
    Humans
    Influenza A Virus, H5N1 Subtype
    Influenza in Birds
    Influenza, Human
    Mice
    Mutation
    RNA Replicase
    Reassortant Viruses
    Viral Proteins
    Virulence

    Pub Type(s)

    Journal Article
    Research Support, N.I.H., Extramural
    Research Support, Non-U.S. Gov't
    Research Support, U.S. Gov't, P.H.S.

    Language

    eng

    PubMed ID

    16269328

    Citation

    Russell, Charles J., and Robert G. Webster. "The Genesis of a Pandemic Influenza Virus." Cell, vol. 123, no. 3, 2005, pp. 368-71.
    Russell CJ, Webster RG. The genesis of a pandemic influenza virus. Cell. 2005;123(3):368-71.
    Russell, C. J., & Webster, R. G. (2005). The genesis of a pandemic influenza virus. Cell, 123(3), pp. 368-71.
    Russell CJ, Webster RG. The Genesis of a Pandemic Influenza Virus. Cell. 2005 Nov 4;123(3):368-71. PubMed PMID: 16269328.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - The genesis of a pandemic influenza virus. AU - Russell,Charles J, AU - Webster,Robert G, PY - 2005/11/5/pubmed PY - 2005/12/21/medline PY - 2005/11/5/entrez SP - 368 EP - 71 JF - Cell JO - Cell VL - 123 IS - 3 N2 - Pandemic influenza viruses pose a significant threat to public health worldwide. In a recent Nature paper, Taubenberger et al. (2005) now report remarkable similarities between the polymerase genes of the influenza virus that caused the 1918 Spanish influenza pandemic and those of avian influenza viruses. Meanwhile, Tumpey et al. (2005) reporting in Science show that the reconstructed 1918 Spanish influenza virus kills mice faster than any other influenza virus so far tested. SN - 0092-8674 UR - https://www.unboundmedicine.com/medline/citation/16269328/The_genesis_of_a_pandemic_influenza_virus_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0092-8674(05)01094-9 DB - PRIME DP - Unbound Medicine ER -