Tags

Type your tag names separated by a space and hit enter

Pathologic subgroups of nonspecific interstitial pneumonia: differential diagnosis from other idiopathic interstitial pneumonias on high-resolution computed tomography.
J Comput Assist Tomogr. 2005 Nov-Dec; 29(6):793-800.JC

Abstract

OBJECTIVE

To determine whether the subtypes of nonspecific interstitial pneumonia (NSIP) could be differentiated from other idiopathic interstitial pneumonias (IIPs) on the basis of findings on high-resolution computed tomography (CT).

METHODS

Two observers evaluated the high-resolution CT findings in 90 patients with IIPs. The patients included 36 with NSIP, 11 with usual interstitial pneumonia (UIP), 8 with cryptogenic organizing pneumonia (COP), 10 with acute interstitial pneumonia (AIP), 14 with desquamative interstitial pneumonia (DIP) or respiratory bronchiolitis-associated interstitial lung disease (RB-ILD), and 11 with lymphoid interstitial pneumonia (LIP). The NSIP cases were subdivided into group 1 NSIP (n = 6), group 2 NSIP (n = 15), and group 3 NSIP (n = 15).

RESULTS

Observers made a correct diagnosis with a high level of confidence in 65% of NSIP cases, 91% of UIP cases, 44% of COP cases, 40% of AIP cases, 32% of DIP or RB-ILD cases, and 82% of LIP cases. Group 1 NSIP was misdiagnosed as AIP, DIP or RB-ILD, and LIP in 8.3% of patients, respectively. Group 2 NSIP was misdiagnosed as COP in 10% of patients, LIP in 6.7%, AIP in 3.3%, and DIP or RB-ILD in 3.3%. Group 3 NSIP was misdiagnosed as UIP in 6.7% of patients, COP in 6.7%, and DIP or RB-ILD in 3.3%.

CONCLUSIONS

In most patients, NSIP can be distinguished from other IIPs based on the findings on high-resolution CT. Only a small percentage of patients with predominantly fibrotic NSIP (group 3 NSIP) show overlap with the high-resolution CT findings of UIP.

Authors+Show Affiliations

Department of Radiology, Osaka University Graduate School of Medicine, Osaka, Japan. tubamoto@radiol.med.osaka-u.ac.jpNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Evaluation Study
Journal Article

Language

eng

PubMed ID

16272854

Citation

Tsubamoto, Mitsuko, et al. "Pathologic Subgroups of Nonspecific Interstitial Pneumonia: Differential Diagnosis From Other Idiopathic Interstitial Pneumonias On High-resolution Computed Tomography." Journal of Computer Assisted Tomography, vol. 29, no. 6, 2005, pp. 793-800.
Tsubamoto M, Müller NL, Johkoh T, et al. Pathologic subgroups of nonspecific interstitial pneumonia: differential diagnosis from other idiopathic interstitial pneumonias on high-resolution computed tomography. J Comput Assist Tomogr. 2005;29(6):793-800.
Tsubamoto, M., Müller, N. L., Johkoh, T., Ichikado, K., Taniguchi, H., Kondoh, Y., Fujimoto, K., Arakawa, H., Koyama, M., Kozuka, T., Inoue, A., Sumikawa, M., Murai, S., Honda, O., Tomiyama, N., Hamada, S., & Nakamura, H. (2005). Pathologic subgroups of nonspecific interstitial pneumonia: differential diagnosis from other idiopathic interstitial pneumonias on high-resolution computed tomography. Journal of Computer Assisted Tomography, 29(6), 793-800.
Tsubamoto M, et al. Pathologic Subgroups of Nonspecific Interstitial Pneumonia: Differential Diagnosis From Other Idiopathic Interstitial Pneumonias On High-resolution Computed Tomography. J Comput Assist Tomogr. 2005 Nov-Dec;29(6):793-800. PubMed PMID: 16272854.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pathologic subgroups of nonspecific interstitial pneumonia: differential diagnosis from other idiopathic interstitial pneumonias on high-resolution computed tomography. AU - Tsubamoto,Mitsuko, AU - Müller,Nestor L, AU - Johkoh,Takeshi, AU - Ichikado,Kazuya, AU - Taniguchi,Hiroyuki, AU - Kondoh,Yasuhiro, AU - Fujimoto,Kiminori, AU - Arakawa,Hiroaki, AU - Koyama,Mitsuhiro, AU - Kozuka,Takenori, AU - Inoue,Atsuo, AU - Sumikawa,Mitsuhiro, AU - Murai,Sachiko, AU - Honda,Osamu, AU - Tomiyama,Noriyuki, AU - Hamada,Seiki, AU - Nakamura,Hironobu, PY - 2005/11/8/pubmed PY - 2005/12/24/medline PY - 2005/11/8/entrez SP - 793 EP - 800 JF - Journal of computer assisted tomography JO - J Comput Assist Tomogr VL - 29 IS - 6 N2 - OBJECTIVE: To determine whether the subtypes of nonspecific interstitial pneumonia (NSIP) could be differentiated from other idiopathic interstitial pneumonias (IIPs) on the basis of findings on high-resolution computed tomography (CT). METHODS: Two observers evaluated the high-resolution CT findings in 90 patients with IIPs. The patients included 36 with NSIP, 11 with usual interstitial pneumonia (UIP), 8 with cryptogenic organizing pneumonia (COP), 10 with acute interstitial pneumonia (AIP), 14 with desquamative interstitial pneumonia (DIP) or respiratory bronchiolitis-associated interstitial lung disease (RB-ILD), and 11 with lymphoid interstitial pneumonia (LIP). The NSIP cases were subdivided into group 1 NSIP (n = 6), group 2 NSIP (n = 15), and group 3 NSIP (n = 15). RESULTS: Observers made a correct diagnosis with a high level of confidence in 65% of NSIP cases, 91% of UIP cases, 44% of COP cases, 40% of AIP cases, 32% of DIP or RB-ILD cases, and 82% of LIP cases. Group 1 NSIP was misdiagnosed as AIP, DIP or RB-ILD, and LIP in 8.3% of patients, respectively. Group 2 NSIP was misdiagnosed as COP in 10% of patients, LIP in 6.7%, AIP in 3.3%, and DIP or RB-ILD in 3.3%. Group 3 NSIP was misdiagnosed as UIP in 6.7% of patients, COP in 6.7%, and DIP or RB-ILD in 3.3%. CONCLUSIONS: In most patients, NSIP can be distinguished from other IIPs based on the findings on high-resolution CT. Only a small percentage of patients with predominantly fibrotic NSIP (group 3 NSIP) show overlap with the high-resolution CT findings of UIP. SN - 0363-8715 UR - https://www.unboundmedicine.com/medline/citation/16272854/Pathologic_subgroups_of_nonspecific_interstitial_pneumonia:_differential_diagnosis_from_other_idiopathic_interstitial_pneumonias_on_high_resolution_computed_tomography_ L2 - http://dx.doi.org/10.1097/01.rct.0000182853.90520.84 DB - PRIME DP - Unbound Medicine ER -