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[Nasopharyngeal and middle ear flora in children with acute otitis media].
Otolaryngol Pol. 2005; 59(4):537-42.OP

Abstract

Nasopharyngeal flora can be a reservoir of bacteria caused acute otitis media in children. The aim of the study was to identify microorganisms and antimicrobial susceptibilities of pathogens from the nasopharynx and middle ear of children with acute otitis media. The study comprised 128 children ages 1 year to 14 years with diagnosed of acute otitis media with purulent discharge. The nasopharyngeal and middle ear samples were collected at the same time. Agar, chocolate, blood and Chapman plates were inoculated for isolation of bacteria. The plates were incubated at 37 degrees C and examined at 24 hours. The susceptibility of bacteria was determined by disk diffusion technique containing concentration gradients for following antibiotics: penicillin, amoxicillin/clavulanate, ampicillin/sulbactam, cefaclor, cefprozil, cefuroxime, erythromycin, azithromycin, clindamycin and trimethoprim/sulfamethoxazole. 196 organisms from nasopharynx and 325 organisms from middle ear were isolated. Most frequent cultured bacteria were: Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis--75.6% in nasopharynx and 77.8% in middle ear. We observed statistically significant (p < 0.01) increased of Moraxella catarrhalis in specimens from the middle ear than from nasopharynx. Most of the organisms were susceptible to amoxicillin/clavulanate--83.2% of bacteria from nasopharynx and 81.8% of bacteria from middle ear. Most organisms were resistant to trimethoprim/sulfamethoxazole--60.7% of bacteria from nasopharynx and 62.6% of bacteria from middle ear. Penicillin resistance was observed in 25.0% of bacteria from nasopharynx and 25.6% of bacteria from middle ear. The correlation in resistance of bacteria between trimethoprim/sulfamethoxazole and erythromycin (r = 0.4886) and between trimethoprim/sulfamethoxazole and penicillin (r = 0.5027) was observed. Nasopharyngeal and middle ear flora in children with acute otitis media is similar. In that case susceptibility of bacteria from the nasopharynx can be useful for empirical treatment of acute otitis media in children.

Authors+Show Affiliations

Szpital Dzieciecy, Oddział Otolaryngologiczny SZPZOZ im. prof. J. Bogdanowicza w Warszawie.No affiliation info available

Pub Type(s)

Journal Article

Language

pol

PubMed ID

16273858

Citation

Zielnik-Jurkiewicz, Beata, and Magdalena Kolczyńska. "[Nasopharyngeal and Middle Ear Flora in Children With Acute Otitis Media]." Otolaryngologia Polska = the Polish Otolaryngology, vol. 59, no. 4, 2005, pp. 537-42.
Zielnik-Jurkiewicz B, Kolczyńska M. [Nasopharyngeal and middle ear flora in children with acute otitis media]. Otolaryngol Pol. 2005;59(4):537-42.
Zielnik-Jurkiewicz, B., & Kolczyńska, M. (2005). [Nasopharyngeal and middle ear flora in children with acute otitis media]. Otolaryngologia Polska = the Polish Otolaryngology, 59(4), 537-42.
Zielnik-Jurkiewicz B, Kolczyńska M. [Nasopharyngeal and Middle Ear Flora in Children With Acute Otitis Media]. Otolaryngol Pol. 2005;59(4):537-42. PubMed PMID: 16273858.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Nasopharyngeal and middle ear flora in children with acute otitis media]. AU - Zielnik-Jurkiewicz,Beata, AU - Kolczyńska,Magdalena, PY - 2005/11/9/pubmed PY - 2006/3/1/medline PY - 2005/11/9/entrez SP - 537 EP - 42 JF - Otolaryngologia polska = The Polish otolaryngology JO - Otolaryngol Pol VL - 59 IS - 4 N2 - Nasopharyngeal flora can be a reservoir of bacteria caused acute otitis media in children. The aim of the study was to identify microorganisms and antimicrobial susceptibilities of pathogens from the nasopharynx and middle ear of children with acute otitis media. The study comprised 128 children ages 1 year to 14 years with diagnosed of acute otitis media with purulent discharge. The nasopharyngeal and middle ear samples were collected at the same time. Agar, chocolate, blood and Chapman plates were inoculated for isolation of bacteria. The plates were incubated at 37 degrees C and examined at 24 hours. The susceptibility of bacteria was determined by disk diffusion technique containing concentration gradients for following antibiotics: penicillin, amoxicillin/clavulanate, ampicillin/sulbactam, cefaclor, cefprozil, cefuroxime, erythromycin, azithromycin, clindamycin and trimethoprim/sulfamethoxazole. 196 organisms from nasopharynx and 325 organisms from middle ear were isolated. Most frequent cultured bacteria were: Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis--75.6% in nasopharynx and 77.8% in middle ear. We observed statistically significant (p < 0.01) increased of Moraxella catarrhalis in specimens from the middle ear than from nasopharynx. Most of the organisms were susceptible to amoxicillin/clavulanate--83.2% of bacteria from nasopharynx and 81.8% of bacteria from middle ear. Most organisms were resistant to trimethoprim/sulfamethoxazole--60.7% of bacteria from nasopharynx and 62.6% of bacteria from middle ear. Penicillin resistance was observed in 25.0% of bacteria from nasopharynx and 25.6% of bacteria from middle ear. The correlation in resistance of bacteria between trimethoprim/sulfamethoxazole and erythromycin (r = 0.4886) and between trimethoprim/sulfamethoxazole and penicillin (r = 0.5027) was observed. Nasopharyngeal and middle ear flora in children with acute otitis media is similar. In that case susceptibility of bacteria from the nasopharynx can be useful for empirical treatment of acute otitis media in children. SN - 0030-6657 UR - https://www.unboundmedicine.com/medline/citation/16273858/[Nasopharyngeal_and_middle_ear_flora_in_children_with_acute_otitis_media]_ L2 - https://medlineplus.gov/antibioticresistance.html DB - PRIME DP - Unbound Medicine ER -