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Clinical review: reunification of acid-base physiology.

Abstract

Recent advances in acid-base physiology and in the epidemiology of acid-base disorders have refined our understanding of the basic control mechanisms that determine blood pH in health and disease. These refinements have also brought parity between the newer, quantitative and older, descriptive approaches to acid-base physiology. This review explores how the new and older approaches to acid-base physiology can be reconciled and combined to result in a powerful bedside tool. A case based tutorial is also provided.

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  • Authors+Show Affiliations

    The CRISMA (Clinical Research Investigation and Systems Modeling of Acute Illness) Laboratory, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

    Source

    Critical care (London, England) 9:5 2005 Oct 5 pg 500-7

    MeSH

    Acid-Base Equilibrium
    Acid-Base Imbalance
    Acidosis, Lactic
    Acute Kidney Injury
    Female
    Humans
    Hydrogen-Ion Concentration
    Middle Aged
    Models, Biological

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    16277739