Tags

Type your tag names separated by a space and hit enter

[Two cases of frontal fibrosing alopecia in postmenopausal women].
J Dtsch Dermatol Ges. 2004 Aug; 2(8):684-6.JD

Abstract

Frontal fibrosing alopecia (FFA) is an uncommon, slowly progressive, cicatricial alopecia which mainly affects postmenopausal women. It is considered to be a variant of lichen planopilaris. We describe two postmenopausal women who developed over 11 and 24 months an asymptomatic atrophic alopecia, restricted to the frontal hairline. The diagnosis of FFA was confirmed by biopsy showing a perifollicular lymphocytic infiltrate with fibrosis. Topical corticosteroids, in one case combined with minoxidil, administered for 3 months arrested the hair loss. The treatment of FFA is often difficult. In most cases, the disease resolves spontaneously after several years. Immunomodulators such as corticosteroids and calcineurin antagonists should be tried in the early stage of FFA (frontal effluvium with perifollicular erythema) in order to arrest the disease in its inflammatory phase.

Authors+Show Affiliations

Herrmann A
Universitätsklinik für Dermatologie und Venerologie der Martin-Luther-Universität Halle-Wittenberg, Halle. anke.herrmann@medizin.uni-halle.de
Bormann G
No affiliation info available
Marsch WC
No affiliation info available
Wohlrab J
No affiliation info available

MeSH

Administration, TopicalAdrenal Cortex HormonesAgedAlopeciaFemaleFibrosisForeheadHumansMiddle AgedPostmenopauseScalpTreatment Outcome

Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

ger

PubMed ID

16279232

Citation

Herrmann, Anke, et al. "[Two Cases of Frontal Fibrosing Alopecia in Postmenopausal Women]." Journal Der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, vol. 2, no. 8, 2004, pp. 684-6.
Herrmann A, Bormann G, Marsch WC, et al. [Two cases of frontal fibrosing alopecia in postmenopausal women]. J Dtsch Dermatol Ges. 2004;2(8):684-6.
Herrmann, A., Bormann, G., Marsch, W. C., & Wohlrab, J. (2004). [Two cases of frontal fibrosing alopecia in postmenopausal women]. Journal Der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2(8), 684-6.
Herrmann A, et al. [Two Cases of Frontal Fibrosing Alopecia in Postmenopausal Women]. J Dtsch Dermatol Ges. 2004;2(8):684-6. PubMed PMID: 16279232.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Two cases of frontal fibrosing alopecia in postmenopausal women]. AU - Herrmann,Anke, AU - Bormann,Gisela, AU - Marsch,Wolfgang Christian, AU - Wohlrab,Johannes, PY - 2005/11/11/pubmed PY - 2005/12/21/medline PY - 2005/11/11/entrez SP - 684 EP - 6 JF - Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG JO - J Dtsch Dermatol Ges VL - 2 IS - 8 N2 - Frontal fibrosing alopecia (FFA) is an uncommon, slowly progressive, cicatricial alopecia which mainly affects postmenopausal women. It is considered to be a variant of lichen planopilaris. We describe two postmenopausal women who developed over 11 and 24 months an asymptomatic atrophic alopecia, restricted to the frontal hairline. The diagnosis of FFA was confirmed by biopsy showing a perifollicular lymphocytic infiltrate with fibrosis. Topical corticosteroids, in one case combined with minoxidil, administered for 3 months arrested the hair loss. The treatment of FFA is often difficult. In most cases, the disease resolves spontaneously after several years. Immunomodulators such as corticosteroids and calcineurin antagonists should be tried in the early stage of FFA (frontal effluvium with perifollicular erythema) in order to arrest the disease in its inflammatory phase. SN - 1610-0379 UR - https://www.unboundmedicine.com/medline/citation/16279232/[Two_cases_of_frontal_fibrosing_alopecia_in_postmenopausal_women]_ DB - PRIME DP - Unbound Medicine ER -