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Prevalence of oral lesions and periodontal diseases in HIV-infected patients on antiretroviral therapy.
Eur J Med Res. 2005 Oct 18; 10(10):448-53.EJ

Abstract

A cross-sectional study examining oral manifestations was carried out in HIV-infected patients of a general HIV-specialized unit to provide prevalence data on oral lesions and periodontal diseases. The occurrence of oral lesions was correlated with demographic and clinical characteristics, immunologic and virologic parameters. Among 139 patients 86% presented any oral lesions with a prevalence of 76% of any periodontal diseases. Most periodontal lesions were classified as conventional gingivitis (28%) or periodontitis (30%). Dental plaque formation was associated with a higher prevalence of periodontal diseases (p = 0.01) and periodontal inflammation scores were higher in patients with more reduced CD4-counts (p = 0.03). Prevalence for HIV-specific oral lesions was 29% with a proportion of 9% of linear gingival erythema (LGE), 3.6% of necrotizing and ulcerative gingivitis (NUG) or periodontitis (NUP), 7% of oral candidiasis, 3.6% of oral hairy leucoplakia (OHL) and single other lesions. HIV-specific lesions (NUG/NUP, oral candidiasis and OHL) were found predominantly in patients with advanced immunosuppression and elevated viral load. Compared with data of oral diseases of the pre-HAART era prevalence of HIV-specific lesions was markedly reduced. Especially frequently known lesions such as oral candidiasis and OHL were less common seen. We noticed a shift of prevalence towards periodontal diseases. Lack of oral hygiene determined by plaque formation and reduced CD4-counts with pronounced periodontal inflammation can be seen as risk factors for periodontal disease. Overall high prevalence of manifestations underlines the importance of oral examination for the general practitioner and visits by oral specialists should become a routine procedure in HIV-patients care.

Authors+Show Affiliations

Clinic for Gastroenterology, Hepatology and Infectious Diseases, University Clinic Düsseldorf, Moorenstr. 5, D-40225 Düsseldorf, Germany. arne.kroidl@med.uni-duesseldorf.deNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16287607

Citation

Kroidl, Arne, et al. "Prevalence of Oral Lesions and Periodontal Diseases in HIV-infected Patients On Antiretroviral Therapy." European Journal of Medical Research, vol. 10, no. 10, 2005, pp. 448-53.
Kroidl A, Schaeben A, Oette M, et al. Prevalence of oral lesions and periodontal diseases in HIV-infected patients on antiretroviral therapy. Eur J Med Res. 2005;10(10):448-53.
Kroidl, A., Schaeben, A., Oette, M., Wettstein, M., Herfordt, A., & Häussinger, D. (2005). Prevalence of oral lesions and periodontal diseases in HIV-infected patients on antiretroviral therapy. European Journal of Medical Research, 10(10), 448-53.
Kroidl A, et al. Prevalence of Oral Lesions and Periodontal Diseases in HIV-infected Patients On Antiretroviral Therapy. Eur J Med Res. 2005 Oct 18;10(10):448-53. PubMed PMID: 16287607.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence of oral lesions and periodontal diseases in HIV-infected patients on antiretroviral therapy. AU - Kroidl,Arne, AU - Schaeben,A, AU - Oette,M, AU - Wettstein,M, AU - Herfordt,A, AU - Häussinger,D, PY - 2005/11/17/pubmed PY - 2005/12/13/medline PY - 2005/11/17/entrez SP - 448 EP - 53 JF - European journal of medical research JO - Eur J Med Res VL - 10 IS - 10 N2 - A cross-sectional study examining oral manifestations was carried out in HIV-infected patients of a general HIV-specialized unit to provide prevalence data on oral lesions and periodontal diseases. The occurrence of oral lesions was correlated with demographic and clinical characteristics, immunologic and virologic parameters. Among 139 patients 86% presented any oral lesions with a prevalence of 76% of any periodontal diseases. Most periodontal lesions were classified as conventional gingivitis (28%) or periodontitis (30%). Dental plaque formation was associated with a higher prevalence of periodontal diseases (p = 0.01) and periodontal inflammation scores were higher in patients with more reduced CD4-counts (p = 0.03). Prevalence for HIV-specific oral lesions was 29% with a proportion of 9% of linear gingival erythema (LGE), 3.6% of necrotizing and ulcerative gingivitis (NUG) or periodontitis (NUP), 7% of oral candidiasis, 3.6% of oral hairy leucoplakia (OHL) and single other lesions. HIV-specific lesions (NUG/NUP, oral candidiasis and OHL) were found predominantly in patients with advanced immunosuppression and elevated viral load. Compared with data of oral diseases of the pre-HAART era prevalence of HIV-specific lesions was markedly reduced. Especially frequently known lesions such as oral candidiasis and OHL were less common seen. We noticed a shift of prevalence towards periodontal diseases. Lack of oral hygiene determined by plaque formation and reduced CD4-counts with pronounced periodontal inflammation can be seen as risk factors for periodontal disease. Overall high prevalence of manifestations underlines the importance of oral examination for the general practitioner and visits by oral specialists should become a routine procedure in HIV-patients care. SN - 0949-2321 UR - https://www.unboundmedicine.com/medline/citation/16287607/Prevalence_of_oral_lesions_and_periodontal_diseases_in_HIV_infected_patients_on_antiretroviral_therapy_ L2 - https://www.diseaseinfosearch.org/result/9735 DB - PRIME DP - Unbound Medicine ER -