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Vascular dementia and Alzheimer's disease: the unsolved problem of clinical and neuropsychological differential diagnosis.
Int J Neurosci. 2005 Dec; 115(12):1657-67.IJ

Abstract

The definition of clinical criteria for differential diagnosis of Vascular Dementia (VaD) and Alzheimer's disease (AD) remains controversial. A large group of patients selected was affected by chronic cerebrovascular disease classified as VaD or not (VND), according to DSM IV criteria. Neuropsychological performances of VaD patients were compared with a group of patients affected by probable AD, matched for age, education, and severity of disease. The comparison of performances did not reach statistical significance in single neuropsychological tasks. The results suggest that neuropsychological examination might not clearly differentiate between VaD and AD patients; the similar pattern of cognitive impairment is probably indicative of several common pathogenetic mechanisms.

Authors+Show Affiliations

Department of Neurology, Catholic University of Sacred Heart, Rome, Italy. sandromisciagna@yahoo.itNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

16287632

Citation

Misciagna, Sandro, et al. "Vascular Dementia and Alzheimer's Disease: the Unsolved Problem of Clinical and Neuropsychological Differential Diagnosis." The International Journal of Neuroscience, vol. 115, no. 12, 2005, pp. 1657-67.
Misciagna S, Masullo C, Giordano A, et al. Vascular dementia and Alzheimer's disease: the unsolved problem of clinical and neuropsychological differential diagnosis. Int J Neurosci. 2005;115(12):1657-67.
Misciagna, S., Masullo, C., Giordano, A., & Silveri, M. C. (2005). Vascular dementia and Alzheimer's disease: the unsolved problem of clinical and neuropsychological differential diagnosis. The International Journal of Neuroscience, 115(12), 1657-67.
Misciagna S, et al. Vascular Dementia and Alzheimer's Disease: the Unsolved Problem of Clinical and Neuropsychological Differential Diagnosis. Int J Neurosci. 2005;115(12):1657-67. PubMed PMID: 16287632.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Vascular dementia and Alzheimer's disease: the unsolved problem of clinical and neuropsychological differential diagnosis. AU - Misciagna,Sandro, AU - Masullo,Carlo, AU - Giordano,Angela, AU - Silveri,M Caterina, PY - 2005/11/17/pubmed PY - 2006/2/8/medline PY - 2005/11/17/entrez SP - 1657 EP - 67 JF - The International journal of neuroscience JO - Int J Neurosci VL - 115 IS - 12 N2 - The definition of clinical criteria for differential diagnosis of Vascular Dementia (VaD) and Alzheimer's disease (AD) remains controversial. A large group of patients selected was affected by chronic cerebrovascular disease classified as VaD or not (VND), according to DSM IV criteria. Neuropsychological performances of VaD patients were compared with a group of patients affected by probable AD, matched for age, education, and severity of disease. The comparison of performances did not reach statistical significance in single neuropsychological tasks. The results suggest that neuropsychological examination might not clearly differentiate between VaD and AD patients; the similar pattern of cognitive impairment is probably indicative of several common pathogenetic mechanisms. SN - 0020-7454 UR - https://www.unboundmedicine.com/medline/citation/16287632/Vascular_dementia_and_Alzheimer's_disease:_the_unsolved_problem_of_clinical_and_neuropsychological_differential_diagnosis_ L2 - https://www.tandfonline.com/doi/full/10.1080/00207450590958501 DB - PRIME DP - Unbound Medicine ER -