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Reemergence of monkeypox: prevalence, diagnostics, and countermeasures.
Clin Infect Dis. 2005 Dec 15; 41(12):1765-71.CI

Abstract

Human monkeypox is a viral zoonotic disease that occurs mostly in the rain forests of central and western Africa. However, the disease recently emerged in the United States in imported wild rodents from Africa. Monkeypox has a clinical presentation very similar to that of ordinary forms of smallpox, including flulike symptoms, fever, malaise, back pain, headache, and characteristic rash. Given this clinical spectrum, differential diagnosis to rule out smallpox is very important. There are no licensed therapies for human monkeypox; however, the smallpox vaccine can protect against the disease. The discontinuation of general vaccination in the 1980s has given rise to increasing susceptibility to monkeypox virus infection in the human population. This has led to fears that monkeypox virus could be used as a bioterrorism agent. Effective prevention relies on limiting the contact with infected patients or animals and limiting the respiratory exposure to infected patients.

Authors+Show Affiliations

Nalca A
United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA. aysegul.nalca@amedd.army.mil
Rimoin AW
No affiliation info available
Bavari S
No affiliation info available
Whitehouse CA
No affiliation info available

MeSH

AnimalsCommunicable Diseases, EmergingDisease OutbreaksHumansMonkeypoxPrevalence

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

16288402

Citation

Nalca, Aysegul, et al. "Reemergence of Monkeypox: Prevalence, Diagnostics, and Countermeasures." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, vol. 41, no. 12, 2005, pp. 1765-71.
Nalca A, Rimoin AW, Bavari S, et al. Reemergence of monkeypox: prevalence, diagnostics, and countermeasures. Clin Infect Dis. 2005;41(12):1765-71.
Nalca, A., Rimoin, A. W., Bavari, S., & Whitehouse, C. A. (2005). Reemergence of monkeypox: prevalence, diagnostics, and countermeasures. Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, 41(12), 1765-71.
Nalca A, et al. Reemergence of Monkeypox: Prevalence, Diagnostics, and Countermeasures. Clin Infect Dis. 2005 Dec 15;41(12):1765-71. PubMed PMID: 16288402.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Reemergence of monkeypox: prevalence, diagnostics, and countermeasures. AU - Nalca,Aysegul, AU - Rimoin,Anne W, AU - Bavari,Sina, AU - Whitehouse,Chris A, Y1 - 2005/11/11/ PY - 2005/6/1/received PY - 2005/7/13/accepted PY - 2005/11/17/pubmed PY - 2006/7/14/medline PY - 2005/11/17/entrez SP - 1765 EP - 71 JF - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America JO - Clin Infect Dis VL - 41 IS - 12 N2 - Human monkeypox is a viral zoonotic disease that occurs mostly in the rain forests of central and western Africa. However, the disease recently emerged in the United States in imported wild rodents from Africa. Monkeypox has a clinical presentation very similar to that of ordinary forms of smallpox, including flulike symptoms, fever, malaise, back pain, headache, and characteristic rash. Given this clinical spectrum, differential diagnosis to rule out smallpox is very important. There are no licensed therapies for human monkeypox; however, the smallpox vaccine can protect against the disease. The discontinuation of general vaccination in the 1980s has given rise to increasing susceptibility to monkeypox virus infection in the human population. This has led to fears that monkeypox virus could be used as a bioterrorism agent. Effective prevention relies on limiting the contact with infected patients or animals and limiting the respiratory exposure to infected patients. SN - 1537-6591 UR - https://www.unboundmedicine.com/medline/citation/16288402/Reemergence_of_monkeypox:_prevalence_diagnostics_and_countermeasures_ DB - PRIME DP - Unbound Medicine ER -