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Laparoscopic azygoportal disconnection procedure with a bipolar feedback controlled sealing system in a porcine model.
J Surg Res. 2006 Jan; 130(1):8-12.JS

Abstract

BACKGROUND

To examine the feasibility of a new, minimally invasive procedure for the devascularization of the proximal stomach and distal esophagus to prevent recurrent variceal bleeding in portal hypertension in a new animal model.

MATERIAL AND METHODS

Portal hypertension was created by laparoscopic clip ligation of the portal vein on 20 pigs. After 2 weeks the azygoportal disconnection procedure was performed with the LigaSure-ATLAS instrument.

RESULTS

There were 16 pigs out of 20 that survived both operations. Two died during introduction of anesthesia, one because of a cardiac arrest (second operation). One pig died resulting from necrosis of the gastric and esophageal wall. Autopsy (2 weeks later) showed that there was a complete arterial devascularization. At autopsy, none of the remaining 16 pigs had esophageal varices or necrosis of the stomach or esophagus.

CONCLUSION

Laparoscopic azygoportal disconnection is a less invasive method for the prevention of rebleeding and seems to be safely performed with the LigaSure-ATLAS instrument.

Authors+Show Affiliations

Ludwig Boltzmann Research Institute for Operative Laparoscopy and 2nd Surgical Department, Academic Teaching Hospital, Linz, Austria. andreas.Shamiyeh@aon.atNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16289598

Citation

Shamiyeh, A, et al. "Laparoscopic Azygoportal Disconnection Procedure With a Bipolar Feedback Controlled Sealing System in a Porcine Model." The Journal of Surgical Research, vol. 130, no. 1, 2006, pp. 8-12.
Shamiyeh A, Hubmann R, Benkö L, et al. Laparoscopic azygoportal disconnection procedure with a bipolar feedback controlled sealing system in a porcine model. J Surg Res. 2006;130(1):8-12.
Shamiyeh, A., Hubmann, R., Benkö, L., Vattay, P., Röth, E., Tulipan, L., Wayand, W. U., & Danis, J. (2006). Laparoscopic azygoportal disconnection procedure with a bipolar feedback controlled sealing system in a porcine model. The Journal of Surgical Research, 130(1), 8-12.
Shamiyeh A, et al. Laparoscopic Azygoportal Disconnection Procedure With a Bipolar Feedback Controlled Sealing System in a Porcine Model. J Surg Res. 2006;130(1):8-12. PubMed PMID: 16289598.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Laparoscopic azygoportal disconnection procedure with a bipolar feedback controlled sealing system in a porcine model. AU - Shamiyeh,A, AU - Hubmann,R, AU - Benkö,L, AU - Vattay,P, AU - Röth,E, AU - Tulipan,L, AU - Wayand,W U, AU - Danis,J, Y1 - 2005/11/14/ PY - 2004/12/18/received PY - 2005/07/02/revised PY - 2005/07/23/accepted PY - 2005/11/18/pubmed PY - 2006/2/16/medline PY - 2005/11/18/entrez SP - 8 EP - 12 JF - The Journal of surgical research JO - J Surg Res VL - 130 IS - 1 N2 - BACKGROUND: To examine the feasibility of a new, minimally invasive procedure for the devascularization of the proximal stomach and distal esophagus to prevent recurrent variceal bleeding in portal hypertension in a new animal model. MATERIAL AND METHODS: Portal hypertension was created by laparoscopic clip ligation of the portal vein on 20 pigs. After 2 weeks the azygoportal disconnection procedure was performed with the LigaSure-ATLAS instrument. RESULTS: There were 16 pigs out of 20 that survived both operations. Two died during introduction of anesthesia, one because of a cardiac arrest (second operation). One pig died resulting from necrosis of the gastric and esophageal wall. Autopsy (2 weeks later) showed that there was a complete arterial devascularization. At autopsy, none of the remaining 16 pigs had esophageal varices or necrosis of the stomach or esophagus. CONCLUSION: Laparoscopic azygoportal disconnection is a less invasive method for the prevention of rebleeding and seems to be safely performed with the LigaSure-ATLAS instrument. SN - 0022-4804 UR - https://www.unboundmedicine.com/medline/citation/16289598/Laparoscopic_azygoportal_disconnection_procedure_with_a_bipolar_feedback_controlled_sealing_system_in_a_porcine_model_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0022-4804(05)00405-1 DB - PRIME DP - Unbound Medicine ER -