Tags

Type your tag names separated by a space and hit enter

Current status and future of implantable insulin pumps for the treatment of diabetes.
Expert Rev Med Devices. 2004 Nov; 1(2):181-5.ER

Abstract

The data from the Diabetes Control and Complications Trial show that control of blood glucose with intensive insulin therapy significantly delays complications of diabetes when compared with conventional therapy consisting of one or two insulin injections per day. However, the subcutaneous intensive insulin therapy, including insulin infusion by external pumps, required to achieve the glycemic goals defined by the Diabetes Control and Complications Trial, led to an increased frequency of severe hypoglycemia. Improvements in parenteral insulin therapy are possible by either modifying subcutaneous insulin kinetics (insulin analogs) or developing better routes of administration. Intraperitoneal insulin infusion offers a more physiologic route of insulin delivery. The ultimate goal for the treatment of diabetes remains the development of a fully automated glucose-controlled device.

Authors+Show Affiliations

University Hospital of Bordeaux, Department of Endocrinology and Diabetes, Bordeaux, France. bogdan.catargi@chu-bordeaux.fr

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

16293038

Citation

Catargi, Bogdan. "Current Status and Future of Implantable Insulin Pumps for the Treatment of Diabetes." Expert Review of Medical Devices, vol. 1, no. 2, 2004, pp. 181-5.
Catargi B. Current status and future of implantable insulin pumps for the treatment of diabetes. Expert Rev Med Devices. 2004;1(2):181-5.
Catargi, B. (2004). Current status and future of implantable insulin pumps for the treatment of diabetes. Expert Review of Medical Devices, 1(2), 181-5.
Catargi B. Current Status and Future of Implantable Insulin Pumps for the Treatment of Diabetes. Expert Rev Med Devices. 2004;1(2):181-5. PubMed PMID: 16293038.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Current status and future of implantable insulin pumps for the treatment of diabetes. A1 - Catargi,Bogdan, PY - 2005/11/19/pubmed PY - 2005/12/15/medline PY - 2005/11/19/entrez SP - 181 EP - 5 JF - Expert review of medical devices JO - Expert Rev Med Devices VL - 1 IS - 2 N2 - The data from the Diabetes Control and Complications Trial show that control of blood glucose with intensive insulin therapy significantly delays complications of diabetes when compared with conventional therapy consisting of one or two insulin injections per day. However, the subcutaneous intensive insulin therapy, including insulin infusion by external pumps, required to achieve the glycemic goals defined by the Diabetes Control and Complications Trial, led to an increased frequency of severe hypoglycemia. Improvements in parenteral insulin therapy are possible by either modifying subcutaneous insulin kinetics (insulin analogs) or developing better routes of administration. Intraperitoneal insulin infusion offers a more physiologic route of insulin delivery. The ultimate goal for the treatment of diabetes remains the development of a fully automated glucose-controlled device. SN - 1743-4440 UR - https://www.unboundmedicine.com/medline/citation/16293038/Current_status_and_future_of_implantable_insulin_pumps_for_the_treatment_of_diabetes_ L2 - https://www.tandfonline.com/doi/full/10.1586/17434440.1.2.181 DB - PRIME DP - Unbound Medicine ER -