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Prevalence of HIV infection and AIDS symptomatology in malnourished children--a hospital based study.
J Commun Dis. 2004 Mar; 36(1):45-52.JC

Abstract

One hundred and seventy five malnourished children aged between 1(1/2) and 12 years attending pediatric department of Regional Institute of Medical Sciences Hospital, Imphal from January 2001 to June 2002 were screened for human immunodeficiency virus (HIV) infection along with their biological mothers after pretest counselling and informed consent. The prevalence rate of HIV seropositivity among malnourished children was 21.7%. Children aged between 1(1/2) and 3 years had the highest seroprevalence (47.4%) and male to female ratio was 1.5: 1. Underweight children showed the highest seroprevalence (47.4%) and children with kwashiorkor showed least seroprevalence (10.5%). Mode of HIV transmission was vertical in 94.7%. The causative agent was HIV-I in all the cases. AIDS defining children features were seen more frequently among HIV seropositive malnourished children as compared to the seronegative children. Prolonged fever (p 0.001), oropharyngeal candidiasis (p<0.001), generalised lymphadenopathy (p<0.001) and disseminated maculopapular dermatitis (p<0.001) were significantly related to HIV infection. Among seronegative children 18.2% fulfilled the clinical criteria for AIDS and among seropositive children 94.7% had AIDS. The total mortality encountered among seropositive children was 34.2%. It is suggested to confirm findings based on larger community based data before recommending mandatory HIV testing in all malnourished children. Specific guidelines on the nutritional management of children with HIV/AIDS is needed in Manipur where HIV is spreading rapidly.

Authors+Show Affiliations

Deptt. of Pediatrics, Regional Institute of Medical Sciences, Imphal, Manipur.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16295686

Citation

Angami, Khriemenuo, et al. "Prevalence of HIV Infection and AIDS Symptomatology in Malnourished Children--a Hospital Based Study." The Journal of Communicable Diseases, vol. 36, no. 1, 2004, pp. 45-52.
Angami K, Reddy SV, Singh KhI, et al. Prevalence of HIV infection and AIDS symptomatology in malnourished children--a hospital based study. J Commun Dis. 2004;36(1):45-52.
Angami, K., Reddy, S. V., Singh, K. h. I., Singh, N. B., & Singh, P. I. (2004). Prevalence of HIV infection and AIDS symptomatology in malnourished children--a hospital based study. The Journal of Communicable Diseases, 36(1), 45-52.
Angami K, et al. Prevalence of HIV Infection and AIDS Symptomatology in Malnourished Children--a Hospital Based Study. J Commun Dis. 2004;36(1):45-52. PubMed PMID: 16295686.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence of HIV infection and AIDS symptomatology in malnourished children--a hospital based study. AU - Angami,Khriemenuo, AU - Reddy,Sudha V R, AU - Singh,Kh Ibochouba, AU - Singh,Ng Brajachand, AU - Singh,P Ibomacha, PY - 2005/11/22/pubmed PY - 2005/12/13/medline PY - 2005/11/22/entrez SP - 45 EP - 52 JF - The Journal of communicable diseases JO - J Commun Dis VL - 36 IS - 1 N2 - One hundred and seventy five malnourished children aged between 1(1/2) and 12 years attending pediatric department of Regional Institute of Medical Sciences Hospital, Imphal from January 2001 to June 2002 were screened for human immunodeficiency virus (HIV) infection along with their biological mothers after pretest counselling and informed consent. The prevalence rate of HIV seropositivity among malnourished children was 21.7%. Children aged between 1(1/2) and 3 years had the highest seroprevalence (47.4%) and male to female ratio was 1.5: 1. Underweight children showed the highest seroprevalence (47.4%) and children with kwashiorkor showed least seroprevalence (10.5%). Mode of HIV transmission was vertical in 94.7%. The causative agent was HIV-I in all the cases. AIDS defining children features were seen more frequently among HIV seropositive malnourished children as compared to the seronegative children. Prolonged fever (p 0.001), oropharyngeal candidiasis (p<0.001), generalised lymphadenopathy (p<0.001) and disseminated maculopapular dermatitis (p<0.001) were significantly related to HIV infection. Among seronegative children 18.2% fulfilled the clinical criteria for AIDS and among seropositive children 94.7% had AIDS. The total mortality encountered among seropositive children was 34.2%. It is suggested to confirm findings based on larger community based data before recommending mandatory HIV testing in all malnourished children. Specific guidelines on the nutritional management of children with HIV/AIDS is needed in Manipur where HIV is spreading rapidly. SN - 0019-5138 UR - https://www.unboundmedicine.com/medline/citation/16295686/Prevalence_of_HIV_infection_and_AIDS_symptomatology_in_malnourished_children__a_hospital_based_study_ DB - PRIME DP - Unbound Medicine ER -