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Associations between ambient, personal, and indoor exposure to fine particulate matter constituents in Dutch and Finnish panels of cardiovascular patients.
Occup Environ Med. 2005 Dec; 62(12):868-77.OE

Abstract

AIMS

To assess the relation between ambient, indoor, and personal levels of PM2.5 and its elemental composition for elderly subjects with cardiovascular disease.

METHODS

In the framework of a European Union funded study, panel studies were conducted in Amsterdam, the Netherlands and Helsinki, Finland. Outdoor PM2.5 concentrations were measured at a fixed site. Each subject's indoor and personal PM2.5 exposure was measured biweekly for six months, during the 24 hour period preceding intensive health measurements. The absorbance of PM2.5 filters was measured as a marker for diesel exhaust. The elemental content of more than 50% of the personal and indoor samples and all corresponding outdoor samples was measured using energy dispersive x ray fluorescence.

RESULTS

For Amsterdam and Helsinki respectively, a total of 225 and 238 personal, and 220 and 233 indoor measurements, were analysed from 36 and 46 subjects. For most elements, personal and indoor concentrations were lower than and highly correlated with outdoor concentrations. The highest correlations (median r>0.9) were found for sulfur and particle absorbance, which both represent fine mode particles from outdoor origin. Low correlations were observed for elements that represent the coarser part of the PM2.5 particles (Ca, Cu, Si, Cl).

CONCLUSIONS

The findings of this study provide support for using fixed site measurements as a measure of exposure to particulate matter in time series studies linking the day to day variation in particulate matter to the day to day variation in health endpoints, especially for components of particulate matter that are generally associated with fine particles and have few indoor sources. The high correlation for absorbance of PM2.5 documents that this applies to particulate matter from combustion sources, such as diesel vehicles, as well.

Authors+Show Affiliations

Division of Environmental and Occupational Health, Institute for Risk Assessment Sciences (IRAS), Utrecht University, The Netherlands. nicole.janssen@rivm.nlNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

16299096

Citation

Janssen, N A H., et al. "Associations Between Ambient, Personal, and Indoor Exposure to Fine Particulate Matter Constituents in Dutch and Finnish Panels of Cardiovascular Patients." Occupational and Environmental Medicine, vol. 62, no. 12, 2005, pp. 868-77.
Janssen NA, Lanki T, Hoek G, et al. Associations between ambient, personal, and indoor exposure to fine particulate matter constituents in Dutch and Finnish panels of cardiovascular patients. Occup Environ Med. 2005;62(12):868-77.
Janssen, N. A., Lanki, T., Hoek, G., Vallius, M., de Hartog, J. J., Van Grieken, R., Pekkanen, J., & Brunekreef, B. (2005). Associations between ambient, personal, and indoor exposure to fine particulate matter constituents in Dutch and Finnish panels of cardiovascular patients. Occupational and Environmental Medicine, 62(12), 868-77.
Janssen NA, et al. Associations Between Ambient, Personal, and Indoor Exposure to Fine Particulate Matter Constituents in Dutch and Finnish Panels of Cardiovascular Patients. Occup Environ Med. 2005;62(12):868-77. PubMed PMID: 16299096.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Associations between ambient, personal, and indoor exposure to fine particulate matter constituents in Dutch and Finnish panels of cardiovascular patients. AU - Janssen,N A H, AU - Lanki,T, AU - Hoek,G, AU - Vallius,M, AU - de Hartog,J J, AU - Van Grieken,R, AU - Pekkanen,J, AU - Brunekreef,B, PY - 2005/11/22/pubmed PY - 2006/2/4/medline PY - 2005/11/22/entrez SP - 868 EP - 77 JF - Occupational and environmental medicine JO - Occup Environ Med VL - 62 IS - 12 N2 - AIMS: To assess the relation between ambient, indoor, and personal levels of PM2.5 and its elemental composition for elderly subjects with cardiovascular disease. METHODS: In the framework of a European Union funded study, panel studies were conducted in Amsterdam, the Netherlands and Helsinki, Finland. Outdoor PM2.5 concentrations were measured at a fixed site. Each subject's indoor and personal PM2.5 exposure was measured biweekly for six months, during the 24 hour period preceding intensive health measurements. The absorbance of PM2.5 filters was measured as a marker for diesel exhaust. The elemental content of more than 50% of the personal and indoor samples and all corresponding outdoor samples was measured using energy dispersive x ray fluorescence. RESULTS: For Amsterdam and Helsinki respectively, a total of 225 and 238 personal, and 220 and 233 indoor measurements, were analysed from 36 and 46 subjects. For most elements, personal and indoor concentrations were lower than and highly correlated with outdoor concentrations. The highest correlations (median r>0.9) were found for sulfur and particle absorbance, which both represent fine mode particles from outdoor origin. Low correlations were observed for elements that represent the coarser part of the PM2.5 particles (Ca, Cu, Si, Cl). CONCLUSIONS: The findings of this study provide support for using fixed site measurements as a measure of exposure to particulate matter in time series studies linking the day to day variation in particulate matter to the day to day variation in health endpoints, especially for components of particulate matter that are generally associated with fine particles and have few indoor sources. The high correlation for absorbance of PM2.5 documents that this applies to particulate matter from combustion sources, such as diesel vehicles, as well. SN - 1470-7926 UR - https://www.unboundmedicine.com/medline/citation/16299096/Associations_between_ambient_personal_and_indoor_exposure_to_fine_particulate_matter_constituents_in_Dutch_and_Finnish_panels_of_cardiovascular_patients_ L2 - https://oem.bmj.com/lookup/pmidlookup?view=long&pmid=16299096 DB - PRIME DP - Unbound Medicine ER -