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The relative effects of corneal thickness and age on Goldmann applanation tonometry and dynamic contour tonometry.
Br J Ophthalmol 2005; 89(12):1572-5BJ

Abstract

AIMS

To establish the effects of central corneal thickness (CCT) on intraocular pressure (IOP) measured with a prototype Pascal dynamic contour tonometer (DCT), to evaluate the effect of CCT and age on the agreement between IOP measured with the Pascal DCT and Goldmann applanation tonometer (GAT), and to compare the interobserver and intraobserver variation of the DCT with the GAT.

METHODS

GAT and DCT IOP measurements were made on 130 eyes of 130 patients and agreement was assessed by means of Bland-Altman plots. The effect of CCT and age on GAT/DCT IOP differences was assessed by linear regression analysis. Interobserver and intraobserver variations for GAT and DCT were assessed in 100 eyes of 100 patients.

RESULTS

The mean difference (95% limits of agreement) between GAT and DCT was -0.7 (-6.3 to 4.9) mm Hg. GAT/DCT IOP differences increased with thicker CCT (slope 0.017 mm Hg/microm, 95% CI 0.004 to 0.03, r2 = 0.05, p = 0.01), and with greater age, slope 0.05 mm Hg/year (95% CI 0.012 to 0.084, r2 = 0.05, p = 0.01). The intraobserver variability of GAT and DCT was 1.7 mm Hg and 3.2 mm Hg, respectively. The interobserver variability was (mean difference (95% limits of agreement)) 0.4 (-3.5 to 4.2) mm Hg for GAT and 0.2 (-4.9 to 5.3) mm Hg for DCT.

CONCLUSIONS

GAT is significantly more affected than DCT by both CCT and subject age. The effect of age suggests an age related corneal biomechanical change that may induce measurement error additional to that of CCT. The prototype DCT has greater measurement variability than the GAT.

Authors+Show Affiliations

Glaucoma Research Unit, Moorfields Eye Hospital, 162 City Road, London EC1V 2PD, UK.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Evaluation Studies
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16299132

Citation

Kotecha, A, et al. "The Relative Effects of Corneal Thickness and Age On Goldmann Applanation Tonometry and Dynamic Contour Tonometry." The British Journal of Ophthalmology, vol. 89, no. 12, 2005, pp. 1572-5.
Kotecha A, White ET, Shewry JM, et al. The relative effects of corneal thickness and age on Goldmann applanation tonometry and dynamic contour tonometry. Br J Ophthalmol. 2005;89(12):1572-5.
Kotecha, A., White, E. T., Shewry, J. M., & Garway-Heath, D. F. (2005). The relative effects of corneal thickness and age on Goldmann applanation tonometry and dynamic contour tonometry. The British Journal of Ophthalmology, 89(12), pp. 1572-5.
Kotecha A, et al. The Relative Effects of Corneal Thickness and Age On Goldmann Applanation Tonometry and Dynamic Contour Tonometry. Br J Ophthalmol. 2005;89(12):1572-5. PubMed PMID: 16299132.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The relative effects of corneal thickness and age on Goldmann applanation tonometry and dynamic contour tonometry. AU - Kotecha,A, AU - White,E T, AU - Shewry,J M, AU - Garway-Heath,D F, PY - 2005/11/22/pubmed PY - 2006/2/4/medline PY - 2005/11/22/entrez SP - 1572 EP - 5 JF - The British journal of ophthalmology JO - Br J Ophthalmol VL - 89 IS - 12 N2 - AIMS: To establish the effects of central corneal thickness (CCT) on intraocular pressure (IOP) measured with a prototype Pascal dynamic contour tonometer (DCT), to evaluate the effect of CCT and age on the agreement between IOP measured with the Pascal DCT and Goldmann applanation tonometer (GAT), and to compare the interobserver and intraobserver variation of the DCT with the GAT. METHODS: GAT and DCT IOP measurements were made on 130 eyes of 130 patients and agreement was assessed by means of Bland-Altman plots. The effect of CCT and age on GAT/DCT IOP differences was assessed by linear regression analysis. Interobserver and intraobserver variations for GAT and DCT were assessed in 100 eyes of 100 patients. RESULTS: The mean difference (95% limits of agreement) between GAT and DCT was -0.7 (-6.3 to 4.9) mm Hg. GAT/DCT IOP differences increased with thicker CCT (slope 0.017 mm Hg/microm, 95% CI 0.004 to 0.03, r2 = 0.05, p = 0.01), and with greater age, slope 0.05 mm Hg/year (95% CI 0.012 to 0.084, r2 = 0.05, p = 0.01). The intraobserver variability of GAT and DCT was 1.7 mm Hg and 3.2 mm Hg, respectively. The interobserver variability was (mean difference (95% limits of agreement)) 0.4 (-3.5 to 4.2) mm Hg for GAT and 0.2 (-4.9 to 5.3) mm Hg for DCT. CONCLUSIONS: GAT is significantly more affected than DCT by both CCT and subject age. The effect of age suggests an age related corneal biomechanical change that may induce measurement error additional to that of CCT. The prototype DCT has greater measurement variability than the GAT. SN - 0007-1161 UR - https://www.unboundmedicine.com/medline/citation/16299132/The_relative_effects_of_corneal_thickness_and_age_on_Goldmann_applanation_tonometry_and_dynamic_contour_tonometry_ L2 - http://bjo.bmj.com/cgi/pmidlookup?view=long&pmid=16299132 DB - PRIME DP - Unbound Medicine ER -