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Gall bladder carcinoma in patients undergoing cholecystectomy for cholelithiasis.
J Pak Med Assoc 2005; 55(11):497-9JP

Abstract

OBJECTIVE

To determine the proportion and timing for suspecting the diagnosis of gall bladder carcinoma in patients undergoing cholecystectomy for cholelithiasis.

METHODS

A retrospective study conducted at the Aga Khan University Hospital, Karachi over a period of six years, included medical records of patients, with cholecystectomy for cholelithiasis and a histopathological diagnosis of gall bladder carcinoma. An extensive review was done with special reference to the features of suspected or unsuspected gall bladder carcinoma. Timing of suspicion was categorized on the basis of clinical features, investigations, operative and histopathological findings.

RESULTS

Out of 1396 cholecystectomies performed during the period of study, sixteen patients (1.15%) were diagnosed as gall bladder carcinoma. Only three patients had pre-operative ultrasonographic features to raise suspicion for gall bladder malignancy whereas eight patients were suspected to have a malignant lesion, on the operative findings. Five patients were missed and the diagnosis was established after histopathological examination.

CONCLUSION

The ultrasonography can miss a significant number of malignant lesions of the gall bladder and every cholecystectomy specimen should be examined histologically.

Authors+Show Affiliations

Department of Surgery, Isra University Hospital, Hyderabad, Sindh.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16304871

Citation

Samad, Abdul. "Gall Bladder Carcinoma in Patients Undergoing Cholecystectomy for Cholelithiasis." JPMA. the Journal of the Pakistan Medical Association, vol. 55, no. 11, 2005, pp. 497-9.
Samad A. Gall bladder carcinoma in patients undergoing cholecystectomy for cholelithiasis. J Pak Med Assoc. 2005;55(11):497-9.
Samad, A. (2005). Gall bladder carcinoma in patients undergoing cholecystectomy for cholelithiasis. JPMA. the Journal of the Pakistan Medical Association, 55(11), pp. 497-9.
Samad A. Gall Bladder Carcinoma in Patients Undergoing Cholecystectomy for Cholelithiasis. J Pak Med Assoc. 2005;55(11):497-9. PubMed PMID: 16304871.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Gall bladder carcinoma in patients undergoing cholecystectomy for cholelithiasis. A1 - Samad,Abdul, PY - 2005/11/25/pubmed PY - 2006/1/24/medline PY - 2005/11/25/entrez SP - 497 EP - 9 JF - JPMA. The Journal of the Pakistan Medical Association JO - J Pak Med Assoc VL - 55 IS - 11 N2 - OBJECTIVE: To determine the proportion and timing for suspecting the diagnosis of gall bladder carcinoma in patients undergoing cholecystectomy for cholelithiasis. METHODS: A retrospective study conducted at the Aga Khan University Hospital, Karachi over a period of six years, included medical records of patients, with cholecystectomy for cholelithiasis and a histopathological diagnosis of gall bladder carcinoma. An extensive review was done with special reference to the features of suspected or unsuspected gall bladder carcinoma. Timing of suspicion was categorized on the basis of clinical features, investigations, operative and histopathological findings. RESULTS: Out of 1396 cholecystectomies performed during the period of study, sixteen patients (1.15%) were diagnosed as gall bladder carcinoma. Only three patients had pre-operative ultrasonographic features to raise suspicion for gall bladder malignancy whereas eight patients were suspected to have a malignant lesion, on the operative findings. Five patients were missed and the diagnosis was established after histopathological examination. CONCLUSION: The ultrasonography can miss a significant number of malignant lesions of the gall bladder and every cholecystectomy specimen should be examined histologically. SN - 0030-9982 UR - https://www.unboundmedicine.com/medline/citation/16304871/Gall_bladder_carcinoma_in_patients_undergoing_cholecystectomy_for_cholelithiasis_ L2 - http://jpma.org.pk/full_article-text.php?article_id=952 DB - PRIME DP - Unbound Medicine ER -