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Adverse reactions to foods.
Med Clin North Am 2006; 90(1):97-127MC

Abstract

Food allergy encompasses a variety of immune-mediated adverse reactions to foods. IgE-mediated, cell-mediated, and mixed-mechanism food allergy disorders are recognized. Over the past 2 decades, the prevalence of food allergy doubled and its phenotypic expression increased in Westernized societies. Major food allergens have been identified for many common foods. Laboratory diagnosis of food allergy relies heavily on the detection of food-specific IgE antibodies, but novel approaches include tests for T-cell-mediated disorders and tests for prediction of tolerance. OFC remains the diagnostic standard for food allergy. Management of food allergy focuses on avoidance of the offending foods, nutritional support, and prompt recognition and treatment of acute food allergic reactions. Anti-IgE monoclonal antibody is the first potential therapy for food allergy that is under-going testing in clinical trials.

Authors+Show Affiliations

Division of Allergy and Immunology, Department of Pediatrics, Mount Sinai School of Medicine, New York, NY 10029, USA.No affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Review

Language

eng

PubMed ID

16310526

Citation

Nowak-Wegrzyn, Anna, and Hugh A. Sampson. "Adverse Reactions to Foods." The Medical Clinics of North America, vol. 90, no. 1, 2006, pp. 97-127.
Nowak-Wegrzyn A, Sampson HA. Adverse reactions to foods. Med Clin North Am. 2006;90(1):97-127.
Nowak-Wegrzyn, A., & Sampson, H. A. (2006). Adverse reactions to foods. The Medical Clinics of North America, 90(1), pp. 97-127.
Nowak-Wegrzyn A, Sampson HA. Adverse Reactions to Foods. Med Clin North Am. 2006;90(1):97-127. PubMed PMID: 16310526.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Adverse reactions to foods. AU - Nowak-Wegrzyn,Anna, AU - Sampson,Hugh A, PY - 2005/11/29/pubmed PY - 2006/2/17/medline PY - 2005/11/29/entrez SP - 97 EP - 127 JF - The Medical clinics of North America JO - Med. Clin. North Am. VL - 90 IS - 1 N2 - Food allergy encompasses a variety of immune-mediated adverse reactions to foods. IgE-mediated, cell-mediated, and mixed-mechanism food allergy disorders are recognized. Over the past 2 decades, the prevalence of food allergy doubled and its phenotypic expression increased in Westernized societies. Major food allergens have been identified for many common foods. Laboratory diagnosis of food allergy relies heavily on the detection of food-specific IgE antibodies, but novel approaches include tests for T-cell-mediated disorders and tests for prediction of tolerance. OFC remains the diagnostic standard for food allergy. Management of food allergy focuses on avoidance of the offending foods, nutritional support, and prompt recognition and treatment of acute food allergic reactions. Anti-IgE monoclonal antibody is the first potential therapy for food allergy that is under-going testing in clinical trials. SN - 0025-7125 UR - https://www.unboundmedicine.com/medline/citation/16310526/full_citation L2 - https://linkinghub.elsevier.com/retrieve/pii/S0025-7125(05)00095-7 DB - PRIME DP - Unbound Medicine ER -