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[Experimental study on influence of acupuncture and moxibustion therapy on apoptosis of colonic epithelial cells in rats of ulcerative colitis].
Zhongguo Zhen Jiu. 2005 Feb; 25(2):119-22.ZZ

Abstract

OBJECTIVE

To study the mechanism of acupuncture and moxibustion in adjusting apoptosis of colonic epithelial cells of the rat of ulcerative colitis (UC).

METHODS

UC rats were randomly divided into four groups including normal control group (NC), model control group (MC), herbs-partitioned moxibustion group (HPM) and electroacupuncture group (EA). The HPM and EA groups were respectively treated with herbs-partitioned moxibustion and electroacupuncture at "Qihai" (CV 6) and bilateral "Tianshu" (ST 25). Then the colon of the rat was taken and the changes of the tissue structure and the cell apoptosis were observed by electron microscope and flow cytometer respectively.

RESULTS

The colon tissue showed histopathological changes, and apoptosis of epithelial cells increased in the model mice of UC as compared with the normal rat. Electroacupuncture and drug-separated moxibustion could significantly decrease the abnormal apoptosis of epithelial cells.

CONCLUSION

The adjustment of the abnormal apoptosis of epithelial cells is one of the mechanisms of drug-separated moxibustion and electroacupuncture treating UC.

Authors+Show Affiliations

Shanghai Research Institute of Acupuncture and Meridian, Shanghai 200030, China. wuhuangan@citiz.netNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

chi

PubMed ID

16312896

Citation

Wu, Huan-gan, et al. "[Experimental Study On Influence of Acupuncture and Moxibustion Therapy On Apoptosis of Colonic Epithelial Cells in Rats of Ulcerative Colitis]." Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, vol. 25, no. 2, 2005, pp. 119-22.
Wu HG, Huang Z, Liu HR, et al. [Experimental study on influence of acupuncture and moxibustion therapy on apoptosis of colonic epithelial cells in rats of ulcerative colitis]. Zhongguo Zhen Jiu. 2005;25(2):119-22.
Wu, H. G., Huang, Z., Liu, H. R., Zhang, W., Shi, Y., Zhu, Y., Cui, Y. H., & Liu, S. M. (2005). [Experimental study on influence of acupuncture and moxibustion therapy on apoptosis of colonic epithelial cells in rats of ulcerative colitis]. Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, 25(2), 119-22.
Wu HG, et al. [Experimental Study On Influence of Acupuncture and Moxibustion Therapy On Apoptosis of Colonic Epithelial Cells in Rats of Ulcerative Colitis]. Zhongguo Zhen Jiu. 2005;25(2):119-22. PubMed PMID: 16312896.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Experimental study on influence of acupuncture and moxibustion therapy on apoptosis of colonic epithelial cells in rats of ulcerative colitis]. AU - Wu,Huan-gan, AU - Huang,Zhen, AU - Liu,Hui-rong, AU - Zhang,Wei, AU - Shi,Yin, AU - Zhu,Yi, AU - Cui,Yun-hua, AU - Liu,Shi-Min, PY - 2005/11/30/pubmed PY - 2016/4/24/medline PY - 2005/11/30/entrez SP - 119 EP - 22 JF - Zhongguo zhen jiu = Chinese acupuncture & moxibustion JO - Zhongguo Zhen Jiu VL - 25 IS - 2 N2 - OBJECTIVE: To study the mechanism of acupuncture and moxibustion in adjusting apoptosis of colonic epithelial cells of the rat of ulcerative colitis (UC). METHODS: UC rats were randomly divided into four groups including normal control group (NC), model control group (MC), herbs-partitioned moxibustion group (HPM) and electroacupuncture group (EA). The HPM and EA groups were respectively treated with herbs-partitioned moxibustion and electroacupuncture at "Qihai" (CV 6) and bilateral "Tianshu" (ST 25). Then the colon of the rat was taken and the changes of the tissue structure and the cell apoptosis were observed by electron microscope and flow cytometer respectively. RESULTS: The colon tissue showed histopathological changes, and apoptosis of epithelial cells increased in the model mice of UC as compared with the normal rat. Electroacupuncture and drug-separated moxibustion could significantly decrease the abnormal apoptosis of epithelial cells. CONCLUSION: The adjustment of the abnormal apoptosis of epithelial cells is one of the mechanisms of drug-separated moxibustion and electroacupuncture treating UC. SN - 0255-2930 UR - https://www.unboundmedicine.com/medline/citation/16312896/[Experimental_study_on_influence_of_acupuncture_and_moxibustion_therapy_on_apoptosis_of_colonic_epithelial_cells_in_rats_of_ulcerative_colitis]_ L2 - http://www.diseaseinfosearch.org/result/7285 DB - PRIME DP - Unbound Medicine ER -