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Clinical characteristics of depressed patients with comorbid diabetes mellitus.

Abstract

Both diabetes and depression are highly prevalent. Patients with diabetes experience higher rates of depression compared to the general population. When present, depression is associated with an increase in the morbidity and mortality of diabetes, suggesting the importance of treatment in this population. The objective of the present study was to characterize depressive characteristics in depressed patients with and without comorbid diabetes. Seventeen patients with type 1 or type 2 diabetes were drawn from outpatient clinical trials. Depressed patients without diabetes were identified from the same studies. Unpaired t-tests and multiple chi-square analyses were used to compare demographic and clinical characteristics between the samples. Diabetic patients in our sample were more depressed and reported lower levels of somatic well-being and contentment compared to non-diabetic patients. The samples did not differ significantly along other dimensions of depression, including course of illness, response to previous treatments and comorbid conditions. These findings suggest that depressed diabetic patients are more similar than not to non-diabetic depressed patients, although important differences exist.

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  • Authors+Show Affiliations

    ,

    Depression Clinical and Research Program, Massachusetts General Hospital, Boston, Massachusetts 02114, USA. tpetersen@partners.org

    , , ,

    Source

    MeSH

    Adolescent
    Adult
    Aged
    Blood Glucose
    Comorbidity
    Depression
    Diabetes Mellitus, Type 1
    Diabetes Mellitus, Type 2
    Female
    Humans
    Male
    Middle Aged
    Psychiatric Status Rating Scales

    Pub Type(s)

    Comparative Study
    Journal Article

    Language

    eng

    PubMed ID

    16317316

    Citation

    Petersen, Timothy, et al. "Clinical Characteristics of Depressed Patients With Comorbid Diabetes Mellitus." International Clinical Psychopharmacology, vol. 21, no. 1, 2006, pp. 43-7.
    Petersen T, Iosifescu DV, Papakostas GI, et al. Clinical characteristics of depressed patients with comorbid diabetes mellitus. Int Clin Psychopharmacol. 2006;21(1):43-7.
    Petersen, T., Iosifescu, D. V., Papakostas, G. I., Shear, D. L., & Fava, M. (2006). Clinical characteristics of depressed patients with comorbid diabetes mellitus. International Clinical Psychopharmacology, 21(1), pp. 43-7.
    Petersen T, et al. Clinical Characteristics of Depressed Patients With Comorbid Diabetes Mellitus. Int Clin Psychopharmacol. 2006;21(1):43-7. PubMed PMID: 16317316.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Clinical characteristics of depressed patients with comorbid diabetes mellitus. AU - Petersen,Timothy, AU - Iosifescu,Dan V, AU - Papakostas,George I, AU - Shear,Deborah L, AU - Fava,Maurizio, PY - 2005/12/1/pubmed PY - 2006/9/20/medline PY - 2005/12/1/entrez SP - 43 EP - 7 JF - International clinical psychopharmacology JO - Int Clin Psychopharmacol VL - 21 IS - 1 N2 - Both diabetes and depression are highly prevalent. Patients with diabetes experience higher rates of depression compared to the general population. When present, depression is associated with an increase in the morbidity and mortality of diabetes, suggesting the importance of treatment in this population. The objective of the present study was to characterize depressive characteristics in depressed patients with and without comorbid diabetes. Seventeen patients with type 1 or type 2 diabetes were drawn from outpatient clinical trials. Depressed patients without diabetes were identified from the same studies. Unpaired t-tests and multiple chi-square analyses were used to compare demographic and clinical characteristics between the samples. Diabetic patients in our sample were more depressed and reported lower levels of somatic well-being and contentment compared to non-diabetic patients. The samples did not differ significantly along other dimensions of depression, including course of illness, response to previous treatments and comorbid conditions. These findings suggest that depressed diabetic patients are more similar than not to non-diabetic depressed patients, although important differences exist. SN - 0268-1315 UR - https://www.unboundmedicine.com/medline/citation/16317316/Clinical_characteristics_of_depressed_patients_with_comorbid_diabetes_mellitus_ L2 - http://Insights.ovid.com/pubmed?pmid=16317316 DB - PRIME DP - Unbound Medicine ER -