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[Penetrating keratoplasty for treatment of fungal keratitis with corneal perforation].
Zhonghua Yan Ke Za Zhi 2005; 41(11):1009-13ZY

Abstract

OBJECTIVE

To evaluate the outcome of penetrating keratoplasty (PKP) for the treatment of fungal keratitis with corneal perforation.

METHODS

40 patients (40 eyes) with corneal perforation secondary to fungal keratitis underwent PKP at Qingdao Eye Hospital from 1994 to 2003. The follow-up ranged from 6-24 months. The postoperative visual acuity and complications were documented.

RESULTS

39 (97.5%) patients preserved the eyeballs. The visual acuity improved in 38 (95.0%) eyes. Fungal infection recurred in 4 eyes, 3 of which were controlled with antifungal medication and 1 was enucleated because of the uncontrolled endophthalmitis. Graft rejection was observed in 15 (37.5%) eyes, 12 of which were cured with medication and 3 received secondary PKP. 3 (7.5%) eyes had graft ulceration, 2 of which were cured and the other one was regrafted because of severe endothelial cell loss. 5 (12.5%) eyes had secondary glaucoma, and the intraocular pressure was controlled medically and surgically. Complicated cataract occurred in 5 (12.5%) eyes, 3 of which underwent cataract extraction. Most complications were controlled successfully. At last follow-up, 36 (90.0%) grafts were clear.

CONCLUSION

PKP is an effective approach for preservation of eyeballs and restoration of visual function in patients eyes with fungal keratitis and corneal perforation.

Authors+Show Affiliations

Qingdao Eye Hospital, Shandong Eye Institute, Qingdao 266071, China. lixinxie@public.qd.sd.cnNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

16318754

Citation

Xie, Li-xin, and Hua-lei Zhai. "[Penetrating Keratoplasty for Treatment of Fungal Keratitis With Corneal Perforation]." [Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology, vol. 41, no. 11, 2005, pp. 1009-13.
Xie LX, Zhai HL. [Penetrating keratoplasty for treatment of fungal keratitis with corneal perforation]. Zhonghua Yan Ke Za Zhi. 2005;41(11):1009-13.
Xie, L. X., & Zhai, H. L. (2005). [Penetrating keratoplasty for treatment of fungal keratitis with corneal perforation]. [Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology, 41(11), pp. 1009-13.
Xie LX, Zhai HL. [Penetrating Keratoplasty for Treatment of Fungal Keratitis With Corneal Perforation]. Zhonghua Yan Ke Za Zhi. 2005;41(11):1009-13. PubMed PMID: 16318754.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Penetrating keratoplasty for treatment of fungal keratitis with corneal perforation]. AU - Xie,Li-xin, AU - Zhai,Hua-lei, PY - 2005/12/2/pubmed PY - 2009/12/30/medline PY - 2005/12/2/entrez SP - 1009 EP - 13 JF - [Zhonghua yan ke za zhi] Chinese journal of ophthalmology JO - Zhonghua Yan Ke Za Zhi VL - 41 IS - 11 N2 - OBJECTIVE: To evaluate the outcome of penetrating keratoplasty (PKP) for the treatment of fungal keratitis with corneal perforation. METHODS: 40 patients (40 eyes) with corneal perforation secondary to fungal keratitis underwent PKP at Qingdao Eye Hospital from 1994 to 2003. The follow-up ranged from 6-24 months. The postoperative visual acuity and complications were documented. RESULTS: 39 (97.5%) patients preserved the eyeballs. The visual acuity improved in 38 (95.0%) eyes. Fungal infection recurred in 4 eyes, 3 of which were controlled with antifungal medication and 1 was enucleated because of the uncontrolled endophthalmitis. Graft rejection was observed in 15 (37.5%) eyes, 12 of which were cured with medication and 3 received secondary PKP. 3 (7.5%) eyes had graft ulceration, 2 of which were cured and the other one was regrafted because of severe endothelial cell loss. 5 (12.5%) eyes had secondary glaucoma, and the intraocular pressure was controlled medically and surgically. Complicated cataract occurred in 5 (12.5%) eyes, 3 of which underwent cataract extraction. Most complications were controlled successfully. At last follow-up, 36 (90.0%) grafts were clear. CONCLUSION: PKP is an effective approach for preservation of eyeballs and restoration of visual function in patients eyes with fungal keratitis and corneal perforation. SN - 0412-4081 UR - https://www.unboundmedicine.com/medline/citation/16318754/[Penetrating_keratoplasty_for_treatment_of_fungal_keratitis_with_corneal_perforation]_ L2 - http://journal.yiigle.com/LinkIn.do?linkin_type=pubmed&issn=0412-4081&year=2005&vol=41&issue=11&fpage=1009 DB - PRIME DP - Unbound Medicine ER -