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Mycoplasma genitalium: prevalence, clinical significance, and transmission.
Sex Transm Infect. 2005 Dec; 81(6):458-62.ST

Abstract

OBJECTIVES

To study the prevalence, symptoms and signs of Mycoplasma genitalium and Chlamydia trachomatis infections in STD clinic attendees and in partners of M genitalium infected patients.

METHODS

M genitalium and C trachomatis were detected by polymerase chain reaction from urethral and endocervical swab specimens in a cross sectional study among 445 female and 501 male STD clinic attendees. Partners of 26 female and 26 male M genitalium positive index patients were examined.

RESULTS

The prevalence of C trachomatis and M genitalium was 4% and 6.3%, respectively, among the women and 5.4% and 6%, respectively, among the men. Dual infections were uncommon. M genitalium was strongly associated with urethritis in both men and women and with cervicitis in women. Among M genitalium infected men, symptomatic urethritis was more common than asymptomatic urethritis. M genitalium and C trachomatis were not associated with symptoms of urethritis or cervicitis in women. Of 26 male partners of M genitalium positive female index patients, 38% were positive, and 77% of the negative partners had symptoms of urethritis. The concordance rate for 22 female partners of male index patients was 45%. For both men and women the M genitalium prevalence was significantly higher in partners of M genitalium positive index patients than in M genitalium negative index patients with urethritis and/or cervicitis.

CONCLUSIONS

M genitalium is associated with urethritis in both men and women and with cervicitis in women. A high concordance rate was found among sexual partners of M genitalium infected patients, indicating that the infection is sexually transmitted.

Authors+Show Affiliations

Department of Venereology, Falu Lasarett, SE-791 82 Falun, Sweden. carin.anagrius@ltdalarna.seNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16326846

Citation

Anagrius, C, et al. "Mycoplasma Genitalium: Prevalence, Clinical Significance, and Transmission." Sexually Transmitted Infections, vol. 81, no. 6, 2005, pp. 458-62.
Anagrius C, Loré B, Jensen JS. Mycoplasma genitalium: prevalence, clinical significance, and transmission. Sex Transm Infect. 2005;81(6):458-62.
Anagrius, C., Loré, B., & Jensen, J. S. (2005). Mycoplasma genitalium: prevalence, clinical significance, and transmission. Sexually Transmitted Infections, 81(6), 458-62.
Anagrius C, Loré B, Jensen JS. Mycoplasma Genitalium: Prevalence, Clinical Significance, and Transmission. Sex Transm Infect. 2005;81(6):458-62. PubMed PMID: 16326846.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Mycoplasma genitalium: prevalence, clinical significance, and transmission. AU - Anagrius,C, AU - Loré,B, AU - Jensen,J S, PY - 2005/12/6/pubmed PY - 2005/12/28/medline PY - 2005/12/6/entrez SP - 458 EP - 62 JF - Sexually transmitted infections JO - Sex Transm Infect VL - 81 IS - 6 N2 - OBJECTIVES: To study the prevalence, symptoms and signs of Mycoplasma genitalium and Chlamydia trachomatis infections in STD clinic attendees and in partners of M genitalium infected patients. METHODS: M genitalium and C trachomatis were detected by polymerase chain reaction from urethral and endocervical swab specimens in a cross sectional study among 445 female and 501 male STD clinic attendees. Partners of 26 female and 26 male M genitalium positive index patients were examined. RESULTS: The prevalence of C trachomatis and M genitalium was 4% and 6.3%, respectively, among the women and 5.4% and 6%, respectively, among the men. Dual infections were uncommon. M genitalium was strongly associated with urethritis in both men and women and with cervicitis in women. Among M genitalium infected men, symptomatic urethritis was more common than asymptomatic urethritis. M genitalium and C trachomatis were not associated with symptoms of urethritis or cervicitis in women. Of 26 male partners of M genitalium positive female index patients, 38% were positive, and 77% of the negative partners had symptoms of urethritis. The concordance rate for 22 female partners of male index patients was 45%. For both men and women the M genitalium prevalence was significantly higher in partners of M genitalium positive index patients than in M genitalium negative index patients with urethritis and/or cervicitis. CONCLUSIONS: M genitalium is associated with urethritis in both men and women and with cervicitis in women. A high concordance rate was found among sexual partners of M genitalium infected patients, indicating that the infection is sexually transmitted. SN - 1368-4973 UR - https://www.unboundmedicine.com/medline/citation/16326846/Mycoplasma_genitalium:_prevalence_clinical_significance_and_transmission_ L2 - https://sti.bmj.com/lookup/pmidlookup?view=long&pmid=16326846 DB - PRIME DP - Unbound Medicine ER -