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Socioeconomic status and C-reactive protein levels in the US population: NHANES IV.
Brain Behav Immun. 2006 Sep; 20(5):498-504.BB

Abstract

C-reactive protein (CRP), a marker of inflammation, has been identified as a risk factor for cardiovascular disease and mortality. Using data on adults aged 20 and over from the fourth National Health and Nutrition Examination Survey, a nationally representative cross-sectional survey, we examined the association between socioeconomic status and CRP in US adults (N=7634). Socioeconomic variation in CRP occurred only at very high levels of CRP (>10.0 mg/L). There was no significant difference in the prevalence of moderate (1.1-3.0 mg/L) or high values of CRP (3.1-10.0mg/L) by socioeconomic status; however, among those with family income at or below the poverty level, 15.7% had very high levels of CRP (greater than 10.0 mg/L), compared to only 9.1% of those in families above the poverty level. Logistic regression results indicate that acute illness, chronic conditions, and differential health behaviors account for about two-thirds of this association. African Americans, Hispanics, and women were more likely to have high levels of CRP. Obesity was the largest risk factor for every level of CRP above normal. Results suggest that differences in very high CRP may be due to factors beyond acute illness and may also reflect chronic health, behavioral and disease processes associated with low socioeconomic status.

Authors+Show Affiliations

Andrus Gerontology Center, University of Southern California, USA. alley@usc.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

16330181

Citation

Alley, Dawn E., et al. "Socioeconomic Status and C-reactive Protein Levels in the US Population: NHANES IV." Brain, Behavior, and Immunity, vol. 20, no. 5, 2006, pp. 498-504.
Alley DE, Seeman TE, Ki Kim J, et al. Socioeconomic status and C-reactive protein levels in the US population: NHANES IV. Brain Behav Immun. 2006;20(5):498-504.
Alley, D. E., Seeman, T. E., Ki Kim, J., Karlamangla, A., Hu, P., & Crimmins, E. M. (2006). Socioeconomic status and C-reactive protein levels in the US population: NHANES IV. Brain, Behavior, and Immunity, 20(5), 498-504.
Alley DE, et al. Socioeconomic Status and C-reactive Protein Levels in the US Population: NHANES IV. Brain Behav Immun. 2006;20(5):498-504. PubMed PMID: 16330181.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Socioeconomic status and C-reactive protein levels in the US population: NHANES IV. AU - Alley,Dawn E, AU - Seeman,Teresa E, AU - Ki Kim,Jung, AU - Karlamangla,Arun, AU - Hu,Peifeng, AU - Crimmins,Eileen M, Y1 - 2005/12/02/ PY - 2005/08/18/received PY - 2005/10/06/revised PY - 2005/10/14/accepted PY - 2005/12/7/pubmed PY - 2006/10/17/medline PY - 2005/12/7/entrez SP - 498 EP - 504 JF - Brain, behavior, and immunity JO - Brain Behav Immun VL - 20 IS - 5 N2 - C-reactive protein (CRP), a marker of inflammation, has been identified as a risk factor for cardiovascular disease and mortality. Using data on adults aged 20 and over from the fourth National Health and Nutrition Examination Survey, a nationally representative cross-sectional survey, we examined the association between socioeconomic status and CRP in US adults (N=7634). Socioeconomic variation in CRP occurred only at very high levels of CRP (>10.0 mg/L). There was no significant difference in the prevalence of moderate (1.1-3.0 mg/L) or high values of CRP (3.1-10.0mg/L) by socioeconomic status; however, among those with family income at or below the poverty level, 15.7% had very high levels of CRP (greater than 10.0 mg/L), compared to only 9.1% of those in families above the poverty level. Logistic regression results indicate that acute illness, chronic conditions, and differential health behaviors account for about two-thirds of this association. African Americans, Hispanics, and women were more likely to have high levels of CRP. Obesity was the largest risk factor for every level of CRP above normal. Results suggest that differences in very high CRP may be due to factors beyond acute illness and may also reflect chronic health, behavioral and disease processes associated with low socioeconomic status. SN - 0889-1591 UR - https://www.unboundmedicine.com/medline/citation/16330181/Socioeconomic_status_and_C_reactive_protein_levels_in_the_US_population:_NHANES_IV_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0889-1591(05)00188-1 DB - PRIME DP - Unbound Medicine ER -