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Extramammary Paget's disease with bowenoid histologic features accompanied by an ectopic lesion on the upper abdomen.
J Dermatol 2005; 32(8):670-3JD

Abstract

We present a 79-year-old man who suffered from extramammary Paget's disease (EMPD) with bowenoid histological features accompanied by an ectopic EMPD lesion on his abdomen. He had had an erythematous plaque on his genital region for three years. Based on a biopsy specimen, he was referred to our hospital with the histological diagnosis of Bowen's disease. The histological findings of the genital lesion obtained by surgical resection showed typical areas of Paget's cells adjacent to areas characteristic of Bowen's disease. Immunohistochemical findings showed CEA and CK7 positive tumor cells in both areas, so the atypical cells showing the bowenoid pattern could be regarded as tumor cells of Paget's disease. Immunohistochemical staining for CEA and CK7 along with multiple biopsies can be helpful in making the diagnosis of Paget's disease with bowenoid histologic features.

Authors+Show Affiliations

Department of Dermatology, Gunma University Graduate School of Medicine, Showamachi, Maebashi, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

16334870

Citation

Nagai, Yayoi, et al. "Extramammary Paget's Disease With Bowenoid Histologic Features Accompanied By an Ectopic Lesion On the Upper Abdomen." The Journal of Dermatology, vol. 32, no. 8, 2005, pp. 670-3.
Nagai Y, Ishibuchi H, Takahashi M, et al. Extramammary Paget's disease with bowenoid histologic features accompanied by an ectopic lesion on the upper abdomen. J Dermatol. 2005;32(8):670-3.
Nagai, Y., Ishibuchi, H., Takahashi, M., Shimizu, A., Matsushima, Y., Tamura, A., & Ishikawa, O. (2005). Extramammary Paget's disease with bowenoid histologic features accompanied by an ectopic lesion on the upper abdomen. The Journal of Dermatology, 32(8), pp. 670-3.
Nagai Y, et al. Extramammary Paget's Disease With Bowenoid Histologic Features Accompanied By an Ectopic Lesion On the Upper Abdomen. J Dermatol. 2005;32(8):670-3. PubMed PMID: 16334870.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Extramammary Paget's disease with bowenoid histologic features accompanied by an ectopic lesion on the upper abdomen. AU - Nagai,Yayoi, AU - Ishibuchi,Hirohisa, AU - Takahashi,Motoi, AU - Shimizu,Akira, AU - Matsushima,Yoichiro, AU - Tamura,Atsushi, AU - Ishikawa,Osamu, PY - 2005/12/13/pubmed PY - 2005/12/24/medline PY - 2005/12/13/entrez SP - 670 EP - 3 JF - The Journal of dermatology JO - J. Dermatol. VL - 32 IS - 8 N2 - We present a 79-year-old man who suffered from extramammary Paget's disease (EMPD) with bowenoid histological features accompanied by an ectopic EMPD lesion on his abdomen. He had had an erythematous plaque on his genital region for three years. Based on a biopsy specimen, he was referred to our hospital with the histological diagnosis of Bowen's disease. The histological findings of the genital lesion obtained by surgical resection showed typical areas of Paget's cells adjacent to areas characteristic of Bowen's disease. Immunohistochemical findings showed CEA and CK7 positive tumor cells in both areas, so the atypical cells showing the bowenoid pattern could be regarded as tumor cells of Paget's disease. Immunohistochemical staining for CEA and CK7 along with multiple biopsies can be helpful in making the diagnosis of Paget's disease with bowenoid histologic features. SN - 0385-2407 UR - https://www.unboundmedicine.com/medline/citation/16334870/Extramammary_Paget's_disease_with_bowenoid_histologic_features_accompanied_by_an_ectopic_lesion_on_the_upper_abdomen_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0385-2407&date=2005&volume=32&issue=8&spage=670 DB - PRIME DP - Unbound Medicine ER -