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[Studies on the chemical constituents in root of Gentiana macrophylla from Shaanxi].
Zhongguo Zhong Yao Za Zhi. 2005 Oct; 30(19):1519-22.ZZ

Abstract

OBJECTIVE

To in vestigate the constituents in root of Gentiana macrophylla.

METHOD

Various column chromatographic techniques were used for isolation and purification of the principles. The structures were elucidated on the basis of spectral data (UV, IR, MS, 1H-, 13C-NMR etc.) and identified by comparing with standard substance.

RESULT

Eight compounds were identified. Four compounds isolated from the chloroform fraction are: 5-carboxyl-3,4-dihydrogen-1H-2-benzopyran-1-one (1), erythrocentauric acid (2), roburic acid (3), oleanolic acid (4). Water fraction gave four known secoiridoid glucosides. They were: gentiopicroside (5), swertiamarine (6), sweroside (7), 6'-O-beta-D-glucosylgentiopicroside (8).

CONCLUSION

1 is a novel compound. It was named as erythrocentauric acid. 2 was isolated from genus Gentiana and 8 was isolated from G. macrophylla for the first time.

Authors+Show Affiliations

Chen QL
School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China. xdyh@yahoo.com.cn
Shi ZY
No affiliation info available
Tu GZ
No affiliation info available
Sun WJ
No affiliation info available

MeSH

GentianaGlucosidesIridoid GlucosidesIridoidsIsocoumarinsMolecular StructurePlant RootsPlants, Medicinal

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

16335823

Citation

Chen, Qian-Liang, et al. "[Studies On the Chemical Constituents in Root of Gentiana Macrophylla From Shaanxi]." Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, vol. 30, no. 19, 2005, pp. 1519-22.
Chen QL, Shi ZY, Tu GZ, et al. [Studies on the chemical constituents in root of Gentiana macrophylla from Shaanxi]. Zhongguo Zhong Yao Za Zhi. 2005;30(19):1519-22.
Chen, Q. L., Shi, Z. Y., Tu, G. Z., & Sun, W. J. (2005). [Studies on the chemical constituents in root of Gentiana macrophylla from Shaanxi]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, 30(19), 1519-22.
Chen QL, et al. [Studies On the Chemical Constituents in Root of Gentiana Macrophylla From Shaanxi]. Zhongguo Zhong Yao Za Zhi. 2005;30(19):1519-22. PubMed PMID: 16335823.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Studies on the chemical constituents in root of Gentiana macrophylla from Shaanxi]. AU - Chen,Qian-Liang, AU - Shi,Zhang-Yan, AU - Tu,Guang-Zhong, AU - Sun,Wen-Ji, PY - 2005/12/13/pubmed PY - 2007/2/8/medline PY - 2005/12/13/entrez SP - 1519 EP - 22 JF - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica JO - Zhongguo Zhong Yao Za Zhi VL - 30 IS - 19 N2 - OBJECTIVE: To in vestigate the constituents in root of Gentiana macrophylla. METHOD: Various column chromatographic techniques were used for isolation and purification of the principles. The structures were elucidated on the basis of spectral data (UV, IR, MS, 1H-, 13C-NMR etc.) and identified by comparing with standard substance. RESULT: Eight compounds were identified. Four compounds isolated from the chloroform fraction are: 5-carboxyl-3,4-dihydrogen-1H-2-benzopyran-1-one (1), erythrocentauric acid (2), roburic acid (3), oleanolic acid (4). Water fraction gave four known secoiridoid glucosides. They were: gentiopicroside (5), swertiamarine (6), sweroside (7), 6'-O-beta-D-glucosylgentiopicroside (8). CONCLUSION: 1 is a novel compound. It was named as erythrocentauric acid. 2 was isolated from genus Gentiana and 8 was isolated from G. macrophylla for the first time. SN - 1001-5302 UR - https://www.unboundmedicine.com/medline/citation/16335823/[Studies_on_the_chemical_constituents_in_root_of_Gentiana_macrophylla_from_Shaanxi]_ DB - PRIME DP - Unbound Medicine ER -