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Perforation of the colon in neonates.
J Pediatr Surg. 2005 Dec; 40(12):1916-9.JP

Abstract

PURPOSE

Gastrointestinal perforation is a catastrophic condition in neonates, especially in premature neonates. Although perforation is commonly observed in the small intestine during the neonatal period, perforation of the colon is a rare condition. This study analyzed the clinical findings and results of perforation of the colon in neonates.

METHODS

Between 1989 and 2004, 8 neonates were treated for spontaneous perforation of the colon at our institute. These patients were retrospectively reviewed.

RESULTS

Gestational ages ranged from 36 to 41 weeks. Seven patients weighed above 2500 g, whereas one patient weighed 1800 g at birth. Perforations developed within 7 days after birth in 6 patients and before birth in two. Associated bowel diseases included rectosigmoid type of Hirschsprung's disease in two patients, immature ganglia in one, imperforate anus in one, colonic atresia in one, and necrotizing enterocolitis in one. An obvious cause was not identified in the remaining two. Six patients without definite anatomic obstructions, such as imperforate anus or colonic atresia, required evaluations for suspected Hirschsprung's disease. All 8 patients underwent colostomy and recovered from peritonitis. Seven survived, but one died of sudden infant death syndrome.

CONCLUSIONS

In this study, perforation of the colon during the neonatal period mostly occurred in term or near-term neonates and carried a good prognosis. During management, it was important to identify Hirschsprung's and its allied disorders as a cause of perforation.

Authors+Show Affiliations

Komuro H
Department of Pediatric Surgery, Graduate School of Comprehensive Human Sciences and University Hospital, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan. hiro-kom@md.tsukuba.ac.jp
Urita Y
No affiliation info available
Hori T
No affiliation info available
Hirai M
No affiliation info available
Kudou S
No affiliation info available
Gotoh C
No affiliation info available
Kawakami H
No affiliation info available
Kaneko M
No affiliation info available

MeSH

Colonic DiseasesColostomyFatal OutcomeFemaleHumansInfant, NewbornIntestinal ObstructionIntestinal PerforationMalePeritonitisPrognosisRetrospective StudiesSudden Infant DeathTreatment Outcome

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

16338318

Citation

Komuro, Hiroaki, et al. "Perforation of the Colon in Neonates." Journal of Pediatric Surgery, vol. 40, no. 12, 2005, pp. 1916-9.
Komuro H, Urita Y, Hori T, et al. Perforation of the colon in neonates. J Pediatr Surg. 2005;40(12):1916-9.
Komuro, H., Urita, Y., Hori, T., Hirai, M., Kudou, S., Gotoh, C., Kawakami, H., & Kaneko, M. (2005). Perforation of the colon in neonates. Journal of Pediatric Surgery, 40(12), 1916-9.
Komuro H, et al. Perforation of the Colon in Neonates. J Pediatr Surg. 2005;40(12):1916-9. PubMed PMID: 16338318.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Perforation of the colon in neonates. AU - Komuro,Hiroaki, AU - Urita,Yasuhisa, AU - Hori,Tetsuo, AU - Hirai,Misako, AU - Kudou,Sumi, AU - Gotoh,Chikashi, AU - Kawakami,Hajime, AU - Kaneko,Michio, PY - 2005/12/13/pubmed PY - 2006/7/19/medline PY - 2005/12/13/entrez SP - 1916 EP - 9 JF - Journal of pediatric surgery JO - J Pediatr Surg VL - 40 IS - 12 N2 - PURPOSE: Gastrointestinal perforation is a catastrophic condition in neonates, especially in premature neonates. Although perforation is commonly observed in the small intestine during the neonatal period, perforation of the colon is a rare condition. This study analyzed the clinical findings and results of perforation of the colon in neonates. METHODS: Between 1989 and 2004, 8 neonates were treated for spontaneous perforation of the colon at our institute. These patients were retrospectively reviewed. RESULTS: Gestational ages ranged from 36 to 41 weeks. Seven patients weighed above 2500 g, whereas one patient weighed 1800 g at birth. Perforations developed within 7 days after birth in 6 patients and before birth in two. Associated bowel diseases included rectosigmoid type of Hirschsprung's disease in two patients, immature ganglia in one, imperforate anus in one, colonic atresia in one, and necrotizing enterocolitis in one. An obvious cause was not identified in the remaining two. Six patients without definite anatomic obstructions, such as imperforate anus or colonic atresia, required evaluations for suspected Hirschsprung's disease. All 8 patients underwent colostomy and recovered from peritonitis. Seven survived, but one died of sudden infant death syndrome. CONCLUSIONS: In this study, perforation of the colon during the neonatal period mostly occurred in term or near-term neonates and carried a good prognosis. During management, it was important to identify Hirschsprung's and its allied disorders as a cause of perforation. SN - 1531-5037 UR - https://www.unboundmedicine.com/medline/citation/16338318/Perforation_of_the_colon_in_neonates_ DB - PRIME DP - Unbound Medicine ER -